Direct comparison between Czerny-Lembert and circular-stapled anastomotic techniques in colorectal anastomosis: A similar pattern of healing for both

Anthony Senagore, Jeffrey W. Milsom, Richard K. Walshaw, Robert Dunston, Irshad H. Chaudry

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

There are scant experimental data directly comparing the healing of the circular-stapled (CS) anastomotic technique with the standard Czerny-Lembert two-layer handsewn (HS) anastomotic technique during the acute and chronic phases of healing. The purpose of this study, therefore, was toseriallyevaluate wound healing in CS and HS anastomoses in the normal porcine colorectum. Forty-two adult female mixed-breed pigs randomly under-went either HS or CS anastomosis at the sacral promontory. Laser Doppler velocimetry (LDV) was used to measure perianastomotic blood flow. Groups of animals under-went a second surgery at 3, 5, 11, 60, or 120 days postoperatively, and anastomoses were restudied using LDV, gross and microscopic grading of inflammation, bursting pressures, and hydroxyproline content. Additionally, the 60-day and 120-day groups of animals under-went preoperative biplanar barium enemas to identify leaks or stenoses. No significant differences in perianastomotic blood flow between the HS and CS techniques were obtained over the entire 120-day study period. Serial evaluation of wound healing revealed no significant differences between the two anastomotic techniques with respect to bursting pressures, gross or microscopic inflammatory scores, or hydroxyproline content. There were no leaks or stenoses with either technique. Despite earlier reports to the contrary, there appears to be no fundamental difference in the mode of healing in the porcine colorectum comparing the HS technique with the CS technique.

Original languageEnglish (US)
Pages (from-to)862-869
Number of pages8
JournalDiseases of the Colon and Rectum
Volume35
Issue number9
DOIs
StatePublished - Sep 1992
Externally publishedYes

Fingerprint

Laser-Doppler Flowmetry
Swine
Hydroxyproline
Wound Healing
Pathologic Constriction
Pressure
Inflammation
Barium Enema

Keywords

  • Anastomotic healing
  • Czerny-Lembert
  • EEA

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Direct comparison between Czerny-Lembert and circular-stapled anastomotic techniques in colorectal anastomosis : A similar pattern of healing for both. / Senagore, Anthony; Milsom, Jeffrey W.; Walshaw, Richard K.; Dunston, Robert; Chaudry, Irshad H.

In: Diseases of the Colon and Rectum, Vol. 35, No. 9, 09.1992, p. 862-869.

Research output: Contribution to journalArticle

Senagore, Anthony ; Milsom, Jeffrey W. ; Walshaw, Richard K. ; Dunston, Robert ; Chaudry, Irshad H. / Direct comparison between Czerny-Lembert and circular-stapled anastomotic techniques in colorectal anastomosis : A similar pattern of healing for both. In: Diseases of the Colon and Rectum. 1992 ; Vol. 35, No. 9. pp. 862-869.
@article{c23a021683fc4524aa6b0f8ac0bfa2dc,
title = "Direct comparison between Czerny-Lembert and circular-stapled anastomotic techniques in colorectal anastomosis: A similar pattern of healing for both",
abstract = "There are scant experimental data directly comparing the healing of the circular-stapled (CS) anastomotic technique with the standard Czerny-Lembert two-layer handsewn (HS) anastomotic technique during the acute and chronic phases of healing. The purpose of this study, therefore, was toseriallyevaluate wound healing in CS and HS anastomoses in the normal porcine colorectum. Forty-two adult female mixed-breed pigs randomly under-went either HS or CS anastomosis at the sacral promontory. Laser Doppler velocimetry (LDV) was used to measure perianastomotic blood flow. Groups of animals under-went a second surgery at 3, 5, 11, 60, or 120 days postoperatively, and anastomoses were restudied using LDV, gross and microscopic grading of inflammation, bursting pressures, and hydroxyproline content. Additionally, the 60-day and 120-day groups of animals under-went preoperative biplanar barium enemas to identify leaks or stenoses. No significant differences in perianastomotic blood flow between the HS and CS techniques were obtained over the entire 120-day study period. Serial evaluation of wound healing revealed no significant differences between the two anastomotic techniques with respect to bursting pressures, gross or microscopic inflammatory scores, or hydroxyproline content. There were no leaks or stenoses with either technique. Despite earlier reports to the contrary, there appears to be no fundamental difference in the mode of healing in the porcine colorectum comparing the HS technique with the CS technique.",
keywords = "Anastomotic healing, Czerny-Lembert, EEA",
author = "Anthony Senagore and Milsom, {Jeffrey W.} and Walshaw, {Richard K.} and Robert Dunston and Chaudry, {Irshad H.}",
year = "1992",
month = "9",
doi = "10.1007/BF02047874",
language = "English (US)",
volume = "35",
pages = "862--869",
journal = "Diseases of the Colon and Rectum",
issn = "0012-3706",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

TY - JOUR

T1 - Direct comparison between Czerny-Lembert and circular-stapled anastomotic techniques in colorectal anastomosis

T2 - A similar pattern of healing for both

AU - Senagore, Anthony

AU - Milsom, Jeffrey W.

AU - Walshaw, Richard K.

AU - Dunston, Robert

AU - Chaudry, Irshad H.

PY - 1992/9

Y1 - 1992/9

N2 - There are scant experimental data directly comparing the healing of the circular-stapled (CS) anastomotic technique with the standard Czerny-Lembert two-layer handsewn (HS) anastomotic technique during the acute and chronic phases of healing. The purpose of this study, therefore, was toseriallyevaluate wound healing in CS and HS anastomoses in the normal porcine colorectum. Forty-two adult female mixed-breed pigs randomly under-went either HS or CS anastomosis at the sacral promontory. Laser Doppler velocimetry (LDV) was used to measure perianastomotic blood flow. Groups of animals under-went a second surgery at 3, 5, 11, 60, or 120 days postoperatively, and anastomoses were restudied using LDV, gross and microscopic grading of inflammation, bursting pressures, and hydroxyproline content. Additionally, the 60-day and 120-day groups of animals under-went preoperative biplanar barium enemas to identify leaks or stenoses. No significant differences in perianastomotic blood flow between the HS and CS techniques were obtained over the entire 120-day study period. Serial evaluation of wound healing revealed no significant differences between the two anastomotic techniques with respect to bursting pressures, gross or microscopic inflammatory scores, or hydroxyproline content. There were no leaks or stenoses with either technique. Despite earlier reports to the contrary, there appears to be no fundamental difference in the mode of healing in the porcine colorectum comparing the HS technique with the CS technique.

AB - There are scant experimental data directly comparing the healing of the circular-stapled (CS) anastomotic technique with the standard Czerny-Lembert two-layer handsewn (HS) anastomotic technique during the acute and chronic phases of healing. The purpose of this study, therefore, was toseriallyevaluate wound healing in CS and HS anastomoses in the normal porcine colorectum. Forty-two adult female mixed-breed pigs randomly under-went either HS or CS anastomosis at the sacral promontory. Laser Doppler velocimetry (LDV) was used to measure perianastomotic blood flow. Groups of animals under-went a second surgery at 3, 5, 11, 60, or 120 days postoperatively, and anastomoses were restudied using LDV, gross and microscopic grading of inflammation, bursting pressures, and hydroxyproline content. Additionally, the 60-day and 120-day groups of animals under-went preoperative biplanar barium enemas to identify leaks or stenoses. No significant differences in perianastomotic blood flow between the HS and CS techniques were obtained over the entire 120-day study period. Serial evaluation of wound healing revealed no significant differences between the two anastomotic techniques with respect to bursting pressures, gross or microscopic inflammatory scores, or hydroxyproline content. There were no leaks or stenoses with either technique. Despite earlier reports to the contrary, there appears to be no fundamental difference in the mode of healing in the porcine colorectum comparing the HS technique with the CS technique.

KW - Anastomotic healing

KW - Czerny-Lembert

KW - EEA

UR - http://www.scopus.com/inward/record.url?scp=0026801466&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026801466&partnerID=8YFLogxK

U2 - 10.1007/BF02047874

DO - 10.1007/BF02047874

M3 - Article

C2 - 1511647

AN - SCOPUS:0026801466

VL - 35

SP - 862

EP - 869

JO - Diseases of the Colon and Rectum

JF - Diseases of the Colon and Rectum

SN - 0012-3706

IS - 9

ER -