Discharge characteristics of fine medial articular afferents at rest and during passive movements of inflamed knee joints

Richard E. Coggeshall, Kyung Ah Park Hong, Lauren A. Langford, Hans Georg Schaible, Robert F. Schmidt

Research output: Contribution to journalArticle

99 Citations (Scopus)

Abstract

After induction of an experimental knee joint inflammation, the activity of single Group III and IV afferent units in the medial articular nerve of the cat was recorded at rest and during passive movements. the properties of these units were compared to those sampled from normal knee joints. The proportion of units displaying resting discharges was higher in the inflamed group. The frequency of discharges was also higher. The receptive fields were larger than those in the control units. Passive movements in the normal working range of the joint activated many more units in the inflamed joint than in the control sample. We conclude that joint inflammation sensitizes articular nociceptors to be active not only at rest, but also during normally innocuous joint movements.

Original languageEnglish (US)
Pages (from-to)185-188
Number of pages4
JournalBrain Research
Volume272
Issue number1
DOIs
StatePublished - Aug 1 1983
Externally publishedYes

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Knee Joint
Joints
Inflammation
Nociceptors
Reference Values
Cats

Keywords

  • group III fiber
  • group IV fiber
  • joint afferent
  • joint inflammation
  • joint nociceptor
  • joint pain
  • knee joint
  • pain

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Discharge characteristics of fine medial articular afferents at rest and during passive movements of inflamed knee joints. / Coggeshall, Richard E.; Ah Park Hong, Kyung; Langford, Lauren A.; Schaible, Hans Georg; Schmidt, Robert F.

In: Brain Research, Vol. 272, No. 1, 01.08.1983, p. 185-188.

Research output: Contribution to journalArticle

Coggeshall, Richard E. ; Ah Park Hong, Kyung ; Langford, Lauren A. ; Schaible, Hans Georg ; Schmidt, Robert F. / Discharge characteristics of fine medial articular afferents at rest and during passive movements of inflamed knee joints. In: Brain Research. 1983 ; Vol. 272, No. 1. pp. 185-188.
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