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Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site

  • Zhiqing Liu
  • , Yi Li
  • , Haiying Chen
  • , Hsien Tsung Lai
  • , Pingyuan Wang
  • , Shwu Yuan Wu
  • , Eric A. Wold
  • , Paul G. Leonard
  • , Sarah Joseph
  • , Haitao Hu
  • , Cheng Ming Chiang
  • , Allan R. Brasier
  • , Bing Tian
  • , Jia Zhou

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Biochemistry, Genetics and Molecular Biology