Diseases associated with altered ryanodine receptor activity

W. J. Durham; X. H.T. Wehrens; S. Sood; S. L. Hamilton

doi:10.1007/978-1-4020-6191-2_10

Diseases associated with altered ryanodine receptor activity

W. J. Durham
, X. H.T. Wehrens
, S. Sood
, S. L. Hamilton

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Mutations in two intracellular Ca²⁺ release channels or ryanodine receptors (RyR1 and RyR2) are associated with a number of human skeletal and cardiac diseases. This chapter discusses these diseases in terms of known mechanisms, controversies, and unanswered questions.

Original language	English (US)
Pages (from-to)	273-321
Number of pages	49
Journal	Subcellular Biochemistry
Volume	45
DOIs	https://doi.org/10.1007/978-1-4020-6191-2_10
State	Published - May 29 2007
Externally published	Yes

Keywords

And atrial fibrillation
And catecholaminergic polymorphic ventricular tachycardia arrhythmogenic right ventricular dysplasia type 2
Calcium homeostasis
Cardiomyopathy
Central core disease
Excitation-contraction coupling
Heart failure
Malignant hyperthermia
Multi-minicore disease
Sudden death

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Cell Biology
Cancer Research

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10.1007/978-1-4020-6191-2_10

Cite this

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abstract = "Mutations in two intracellular Ca2+ release channels or ryanodine receptors (RyR1 and RyR2) are associated with a number of human skeletal and cardiac diseases. This chapter discusses these diseases in terms of known mechanisms, controversies, and unanswered questions.",

keywords = "And atrial fibrillation, And catecholaminergic polymorphic ventricular tachycardia arrhythmogenic right ventricular dysplasia type 2, Calcium homeostasis, Cardiomyopathy, Central core disease, Excitation-contraction coupling, Heart failure, Malignant hyperthermia, Multi-minicore disease, Sudden death",

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AU - Durham, W. J.

AU - Wehrens, X. H.T.

AU - Sood, S.

AU - Hamilton, S. L.

PY - 2007/5/29

Y1 - 2007/5/29

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AB - Mutations in two intracellular Ca2+ release channels or ryanodine receptors (RyR1 and RyR2) are associated with a number of human skeletal and cardiac diseases. This chapter discusses these diseases in terms of known mechanisms, controversies, and unanswered questions.

KW - And atrial fibrillation

KW - And catecholaminergic polymorphic ventricular tachycardia arrhythmogenic right ventricular dysplasia type 2

KW - Calcium homeostasis

KW - Cardiomyopathy

KW - Central core disease

KW - Excitation-contraction coupling

KW - Heart failure

KW - Malignant hyperthermia

KW - Multi-minicore disease

KW - Sudden death

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SP - 273

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JO - Subcellular Biochemistry

JF - Subcellular Biochemistry

ER -

Diseases associated with altered ryanodine receptor activity

Abstract

Keywords

ASJC Scopus subject areas

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