Disseminated Pseudallescheria boydii (Scedosporium apiospermum) infection in a renal transplant patient

E. L. Campagnaro, K. J. Woodside, M. G. Early, Kristene Gugliuzza, M. I. Colomé-Grimmer, F. A. Lopez, John A. Daller

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Transplant recipients receive a number of immunosuppressive medications that result in an increased risk of infection, including infections with microbes that are normally not pathogenic. We describe a patient with end-stage renal disease who underwent kidney transplantation. Six months postoperatively, he presented with a lesion on his ankle, multiple thigh nodules, and right testicular pain. Biopsy of the ankle lesion demonstrated Pseudallescheria boydii (Scedosporium apiospermum), a common environmental fungus. Following orchiectomy, multiple fungal elements were found that were initially described as Aspergillus species, but later identified as P. boydii. In addition, multiple brain abscesses were found on magnetic resonance imaging. Despite treatment with multiple antifungal medications, the patient died of cardiac dysrhythmia. Current diagnostic and therapeutic alternatives for P. boydii are reviewed.

Original languageEnglish (US)
Pages (from-to)207-211
Number of pages5
JournalTransplant Infectious Disease
Volume4
Issue number4
StatePublished - Dec 2002

Fingerprint

Pseudallescheria
Scedosporium
Ankle
Transplants
Kidney
Brain Abscess
Orchiectomy
Aspergillus
Immunosuppressive Agents
Thigh
Infection
Kidney Transplantation
Chronic Kidney Failure
Cardiac Arrhythmias
Fungi
Magnetic Resonance Imaging
Biopsy
Pain
Therapeutics

Keywords

  • Azole
  • Fungal abscess
  • Fungal infection
  • Pseudallescheria boydii
  • Pseudallescheriasis
  • Scedosporium apiospermum
  • Voriconazole

ASJC Scopus subject areas

  • Transplantation
  • Microbiology (medical)
  • Immunology

Cite this

Campagnaro, E. L., Woodside, K. J., Early, M. G., Gugliuzza, K., Colomé-Grimmer, M. I., Lopez, F. A., & Daller, J. A. (2002). Disseminated Pseudallescheria boydii (Scedosporium apiospermum) infection in a renal transplant patient. Transplant Infectious Disease, 4(4), 207-211.

Disseminated Pseudallescheria boydii (Scedosporium apiospermum) infection in a renal transplant patient. / Campagnaro, E. L.; Woodside, K. J.; Early, M. G.; Gugliuzza, Kristene; Colomé-Grimmer, M. I.; Lopez, F. A.; Daller, John A.

In: Transplant Infectious Disease, Vol. 4, No. 4, 12.2002, p. 207-211.

Research output: Contribution to journalArticle

Campagnaro, EL, Woodside, KJ, Early, MG, Gugliuzza, K, Colomé-Grimmer, MI, Lopez, FA & Daller, JA 2002, 'Disseminated Pseudallescheria boydii (Scedosporium apiospermum) infection in a renal transplant patient', Transplant Infectious Disease, vol. 4, no. 4, pp. 207-211.
Campagnaro EL, Woodside KJ, Early MG, Gugliuzza K, Colomé-Grimmer MI, Lopez FA et al. Disseminated Pseudallescheria boydii (Scedosporium apiospermum) infection in a renal transplant patient. Transplant Infectious Disease. 2002 Dec;4(4):207-211.
Campagnaro, E. L. ; Woodside, K. J. ; Early, M. G. ; Gugliuzza, Kristene ; Colomé-Grimmer, M. I. ; Lopez, F. A. ; Daller, John A. / Disseminated Pseudallescheria boydii (Scedosporium apiospermum) infection in a renal transplant patient. In: Transplant Infectious Disease. 2002 ; Vol. 4, No. 4. pp. 207-211.
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