Abstract
Oral tissue samples were studied using mid-IR fiber-optic attenuated total reflectance spectroscopy and other spectral techniques. The 1745 cm-1 band, which is assigned to the ester group (C=O) vibration of triglycerides, is a reliable marker that is present in normal tissues but absent or a weak band in malignant oral tissues. Other bands such as C-H stretching bands and the amide bands are also helpful in distinguishing malignant tissues from normal tissues. Subtraction spectra confirmed the above conclusion. In addition, Raman spectroscopic measurements were in agreement with the results observed from FTIR spectra.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 185-192 |
| Number of pages | 8 |
| Journal | Biopolymers - Biospectroscopy Section |
| Volume | 62 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2001 |
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Keywords
- Cancer
- Diagnosis
- Fiber optics
- FTIR
- Oral tissue
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Biophysics
Cite this
Distinguishing malignant from normal oral tissues using FTIR fiber-optic techniques. / Wu, Jin Guang; Xu, Yi Zhuang; Sun, Cuan Wen; Soloway, Roger D.; Xu, Duan Fu; Wu, Qi Guang; Sun, Kai Hua; Weng, Shi Fu; Xu, Guang Xian.
In: Biopolymers - Biospectroscopy Section, Vol. 62, No. 4, 2001, p. 185-192.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Distinguishing malignant from normal oral tissues using FTIR fiber-optic techniques
AU - Wu, Jin Guang
AU - Xu, Yi Zhuang
AU - Sun, Cuan Wen
AU - Soloway, Roger D.
AU - Xu, Duan Fu
AU - Wu, Qi Guang
AU - Sun, Kai Hua
AU - Weng, Shi Fu
AU - Xu, Guang Xian
PY - 2001
Y1 - 2001
N2 - Oral tissue samples were studied using mid-IR fiber-optic attenuated total reflectance spectroscopy and other spectral techniques. The 1745 cm-1 band, which is assigned to the ester group (C=O) vibration of triglycerides, is a reliable marker that is present in normal tissues but absent or a weak band in malignant oral tissues. Other bands such as C-H stretching bands and the amide bands are also helpful in distinguishing malignant tissues from normal tissues. Subtraction spectra confirmed the above conclusion. In addition, Raman spectroscopic measurements were in agreement with the results observed from FTIR spectra.
AB - Oral tissue samples were studied using mid-IR fiber-optic attenuated total reflectance spectroscopy and other spectral techniques. The 1745 cm-1 band, which is assigned to the ester group (C=O) vibration of triglycerides, is a reliable marker that is present in normal tissues but absent or a weak band in malignant oral tissues. Other bands such as C-H stretching bands and the amide bands are also helpful in distinguishing malignant tissues from normal tissues. Subtraction spectra confirmed the above conclusion. In addition, Raman spectroscopic measurements were in agreement with the results observed from FTIR spectra.
KW - Cancer
KW - Diagnosis
KW - Fiber optics
KW - FTIR
KW - Oral tissue
UR - http://www.scopus.com/inward/record.url?scp=0034968559&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034968559&partnerID=8YFLogxK
U2 - 10.1002/bip.1013
DO - 10.1002/bip.1013
M3 - Article
C2 - 11391568
AN - SCOPUS:0034968559
VL - 62
SP - 185
EP - 192
JO - Biopolymers
JF - Biopolymers
SN - 0006-3525
IS - 4
ER -