Does the maxillary division of the trigeminal nerve traverse the cavernous sinus? An anatomical study and review of the literature

R. Shane Tubbs, Mark Hill, William R. May, Erik Middlebrooks, Selma Z. Kominek, Nick Marchase, Mohammadali Mohajel Shoja, Marios Loukas, W. Jerry Oakes

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Aim: Many authors have included the V2 segment of the trigeminal nerve as a component of the cavernous sinus. However, many authorities have stated that this part of the fifth cranial nerve is not within this intracranial venous sinus. Materials and methods: To further elucidate this potentially important relationship, 10 fresh cadaveric heads underwent injection of the cavernous sinus with blue latex or a cresyl-violet solution. Subsequent sectioning in the coronal plane in 1 cm sections from the level of the trigeminal ganglia anteriorly to the level of the superior orbital fissure was made. Observations were then made between the relationships of the cavernous sinus and the V2 nerve. Results: On all 20 sides, the V2 segment of the trigeminal nerve did not have filling of latex or cresyl-violet mixture lateral to it thus implying that this part of the trigeminal nerve is not found within the cavernous sinus. Two sides did demonstrate an emissary vein that traveled with the V2 part of the trigeminal nerve through the foramen rotundum toward the cavernous sinus. Conclusions: Based on our findings, the V2 part of the trigeminal nerve is not found bathed with venous blood within the cavernous sinus. Reports that state the contrary may have confused laterally positioned emissary veins as being part of the cavernous sinus and therefore erroneously concluded that V2 was within this cranial venous sinus. These data may prove useful to neurosurgeons that operate in the region of the cavernous sinus or to radiologists who interpret imaging of this area.

Original languageEnglish (US)
Pages (from-to)37-40
Number of pages4
JournalSurgical and Radiologic Anatomy
Volume30
Issue number1
DOIs
StatePublished - Feb 1 2008
Externally publishedYes

Fingerprint

Cavernous Sinus
Trigeminal Nerve
Cranial Sinuses
Latex
Veins
Trigeminal Ganglion
Head
Injections

Keywords

  • Anatomy
  • Cavernous sinus
  • Cranium
  • Trigeminal nerve
  • V2
  • Venous sinus

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Does the maxillary division of the trigeminal nerve traverse the cavernous sinus? An anatomical study and review of the literature. / Tubbs, R. Shane; Hill, Mark; May, William R.; Middlebrooks, Erik; Kominek, Selma Z.; Marchase, Nick; Mohajel Shoja, Mohammadali; Loukas, Marios; Oakes, W. Jerry.

In: Surgical and Radiologic Anatomy, Vol. 30, No. 1, 01.02.2008, p. 37-40.

Research output: Contribution to journalReview article

Tubbs, RS, Hill, M, May, WR, Middlebrooks, E, Kominek, SZ, Marchase, N, Mohajel Shoja, M, Loukas, M & Oakes, WJ 2008, 'Does the maxillary division of the trigeminal nerve traverse the cavernous sinus? An anatomical study and review of the literature', Surgical and Radiologic Anatomy, vol. 30, no. 1, pp. 37-40. https://doi.org/10.1007/s00276-007-0280-7
Tubbs, R. Shane ; Hill, Mark ; May, William R. ; Middlebrooks, Erik ; Kominek, Selma Z. ; Marchase, Nick ; Mohajel Shoja, Mohammadali ; Loukas, Marios ; Oakes, W. Jerry. / Does the maxillary division of the trigeminal nerve traverse the cavernous sinus? An anatomical study and review of the literature. In: Surgical and Radiologic Anatomy. 2008 ; Vol. 30, No. 1. pp. 37-40.
@article{7c9d2ecfba1e44959584defd60cacffd,
title = "Does the maxillary division of the trigeminal nerve traverse the cavernous sinus? An anatomical study and review of the literature",
abstract = "Aim: Many authors have included the V2 segment of the trigeminal nerve as a component of the cavernous sinus. However, many authorities have stated that this part of the fifth cranial nerve is not within this intracranial venous sinus. Materials and methods: To further elucidate this potentially important relationship, 10 fresh cadaveric heads underwent injection of the cavernous sinus with blue latex or a cresyl-violet solution. Subsequent sectioning in the coronal plane in 1 cm sections from the level of the trigeminal ganglia anteriorly to the level of the superior orbital fissure was made. Observations were then made between the relationships of the cavernous sinus and the V2 nerve. Results: On all 20 sides, the V2 segment of the trigeminal nerve did not have filling of latex or cresyl-violet mixture lateral to it thus implying that this part of the trigeminal nerve is not found within the cavernous sinus. Two sides did demonstrate an emissary vein that traveled with the V2 part of the trigeminal nerve through the foramen rotundum toward the cavernous sinus. Conclusions: Based on our findings, the V2 part of the trigeminal nerve is not found bathed with venous blood within the cavernous sinus. Reports that state the contrary may have confused laterally positioned emissary veins as being part of the cavernous sinus and therefore erroneously concluded that V2 was within this cranial venous sinus. These data may prove useful to neurosurgeons that operate in the region of the cavernous sinus or to radiologists who interpret imaging of this area.",
keywords = "Anatomy, Cavernous sinus, Cranium, Trigeminal nerve, V2, Venous sinus",
author = "Tubbs, {R. Shane} and Mark Hill and May, {William R.} and Erik Middlebrooks and Kominek, {Selma Z.} and Nick Marchase and {Mohajel Shoja}, Mohammadali and Marios Loukas and Oakes, {W. Jerry}",
year = "2008",
month = "2",
day = "1",
doi = "10.1007/s00276-007-0280-7",
language = "English (US)",
volume = "30",
pages = "37--40",
journal = "Surgical and Radiologic Anatomy",
issn = "0930-1038",
publisher = "Springer Paris",
number = "1",

}

TY - JOUR

T1 - Does the maxillary division of the trigeminal nerve traverse the cavernous sinus? An anatomical study and review of the literature

AU - Tubbs, R. Shane

AU - Hill, Mark

AU - May, William R.

AU - Middlebrooks, Erik

AU - Kominek, Selma Z.

AU - Marchase, Nick

AU - Mohajel Shoja, Mohammadali

AU - Loukas, Marios

AU - Oakes, W. Jerry

PY - 2008/2/1

Y1 - 2008/2/1

N2 - Aim: Many authors have included the V2 segment of the trigeminal nerve as a component of the cavernous sinus. However, many authorities have stated that this part of the fifth cranial nerve is not within this intracranial venous sinus. Materials and methods: To further elucidate this potentially important relationship, 10 fresh cadaveric heads underwent injection of the cavernous sinus with blue latex or a cresyl-violet solution. Subsequent sectioning in the coronal plane in 1 cm sections from the level of the trigeminal ganglia anteriorly to the level of the superior orbital fissure was made. Observations were then made between the relationships of the cavernous sinus and the V2 nerve. Results: On all 20 sides, the V2 segment of the trigeminal nerve did not have filling of latex or cresyl-violet mixture lateral to it thus implying that this part of the trigeminal nerve is not found within the cavernous sinus. Two sides did demonstrate an emissary vein that traveled with the V2 part of the trigeminal nerve through the foramen rotundum toward the cavernous sinus. Conclusions: Based on our findings, the V2 part of the trigeminal nerve is not found bathed with venous blood within the cavernous sinus. Reports that state the contrary may have confused laterally positioned emissary veins as being part of the cavernous sinus and therefore erroneously concluded that V2 was within this cranial venous sinus. These data may prove useful to neurosurgeons that operate in the region of the cavernous sinus or to radiologists who interpret imaging of this area.

AB - Aim: Many authors have included the V2 segment of the trigeminal nerve as a component of the cavernous sinus. However, many authorities have stated that this part of the fifth cranial nerve is not within this intracranial venous sinus. Materials and methods: To further elucidate this potentially important relationship, 10 fresh cadaveric heads underwent injection of the cavernous sinus with blue latex or a cresyl-violet solution. Subsequent sectioning in the coronal plane in 1 cm sections from the level of the trigeminal ganglia anteriorly to the level of the superior orbital fissure was made. Observations were then made between the relationships of the cavernous sinus and the V2 nerve. Results: On all 20 sides, the V2 segment of the trigeminal nerve did not have filling of latex or cresyl-violet mixture lateral to it thus implying that this part of the trigeminal nerve is not found within the cavernous sinus. Two sides did demonstrate an emissary vein that traveled with the V2 part of the trigeminal nerve through the foramen rotundum toward the cavernous sinus. Conclusions: Based on our findings, the V2 part of the trigeminal nerve is not found bathed with venous blood within the cavernous sinus. Reports that state the contrary may have confused laterally positioned emissary veins as being part of the cavernous sinus and therefore erroneously concluded that V2 was within this cranial venous sinus. These data may prove useful to neurosurgeons that operate in the region of the cavernous sinus or to radiologists who interpret imaging of this area.

KW - Anatomy

KW - Cavernous sinus

KW - Cranium

KW - Trigeminal nerve

KW - V2

KW - Venous sinus

UR - http://www.scopus.com/inward/record.url?scp=49049101391&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=49049101391&partnerID=8YFLogxK

U2 - 10.1007/s00276-007-0280-7

DO - 10.1007/s00276-007-0280-7

M3 - Review article

VL - 30

SP - 37

EP - 40

JO - Surgical and Radiologic Anatomy

JF - Surgical and Radiologic Anatomy

SN - 0930-1038

IS - 1

ER -