Domestic cases of hemorrhagic fever with renal syndrome in the United States

G. E. Glass, A. J. Watson, J. W. LeDuc, J. E. Childs

Research output: Contribution to journalArticle

61 Scopus citations

Abstract

Although serologic studies have identified hantaviral infection in the United States, acute disease has not been recognized. This study describes 3 cases of domestically acquired hemorrhagic fever with renal syndrome (HFRS) in the United States. Infection was due to a local strain of Seoul virus (Baltimore rat virus). A review of the clinical features indicated a mild illness characterized by nausea, vomiting, renal and liver failure similar to HFRS described elsewhere for rat-borne viruses. Follow-up of 2 patients identified persitent hypertension and renal disease providing further evidence of an association between past hantaviral infection and hypertensive renal disease.

Original languageEnglish (US)
Pages (from-to)48-51
Number of pages4
JournalNephron
Volume68
Issue number1
DOIs
StatePublished - Jan 1 1994
Externally publishedYes

Keywords

  • Chronic renal disease
  • Hantavirus
  • Hemorrhagic fever with renal syndrome
  • Hypertensive renal disease

ASJC Scopus subject areas

  • Physiology
  • Nephrology
  • Physiology (medical)
  • Urology

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