Donor safety and remnant liver volume in living donor liver transplantation

C. Burcin Taner, Murat Dayangac, Baris Akin, Deniz Balci, Suleyman Uraz, Cihan Duran, Refik Killi, Omer Ayanoglu, Yildiray Yuzer, Yaman Tokat

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Living donor liver transplantation is now a common practice in countries in which the availability of cadaveric organs is limited. The preoperative preparation, intraoperative surgical technique, and postoperative care of donors and recipients have evolved in recent years. We retrospectively compared 67 donors with a remnant liver volume equal to or more than 30% (group 1) with 14 donors who had less than 30% remnant liver volume (group 2) for donor outcomes. All the complications in donors were systematically classified. Donors with less than 30% remnant liver volume showed significantly higher peak aspartate aminotransferase, alanine aminotransferase, international normalized ratio, and bilirubin levels. There were 6 complications in group 1 and 4 complications in group 2. The difference between the 2 groups in terms of donor complications did reach statistical significance (P = 0.043); donors with a remnant liver volume < 30% had a 4 times greater relative risk of morbidity. In conclusion, the use of donors with less than 30% Tmnant liver volume is highly debatable as donor safety should be of utmost importance in living donor liver transplantation.

Original languageEnglish (US)
Pages (from-to)1174-1179
Number of pages6
JournalLiver Transplantation
Volume14
Issue number8
DOIs
StatePublished - Aug 1 2008
Externally publishedYes

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Living Donors
Liver Transplantation
Tissue Donors
Safety
Liver
International Normalized Ratio
Postoperative Care
Aspartate Aminotransferases
Alanine Transaminase
Bilirubin
Morbidity

ASJC Scopus subject areas

  • Surgery
  • Hepatology
  • Transplantation

Cite this

Taner, C. B., Dayangac, M., Akin, B., Balci, D., Uraz, S., Duran, C., ... Tokat, Y. (2008). Donor safety and remnant liver volume in living donor liver transplantation. Liver Transplantation, 14(8), 1174-1179. https://doi.org/10.1002/lt.21562

Donor safety and remnant liver volume in living donor liver transplantation. / Taner, C. Burcin; Dayangac, Murat; Akin, Baris; Balci, Deniz; Uraz, Suleyman; Duran, Cihan; Killi, Refik; Ayanoglu, Omer; Yuzer, Yildiray; Tokat, Yaman.

In: Liver Transplantation, Vol. 14, No. 8, 01.08.2008, p. 1174-1179.

Research output: Contribution to journalArticle

Taner, CB, Dayangac, M, Akin, B, Balci, D, Uraz, S, Duran, C, Killi, R, Ayanoglu, O, Yuzer, Y & Tokat, Y 2008, 'Donor safety and remnant liver volume in living donor liver transplantation', Liver Transplantation, vol. 14, no. 8, pp. 1174-1179. https://doi.org/10.1002/lt.21562
Taner, C. Burcin ; Dayangac, Murat ; Akin, Baris ; Balci, Deniz ; Uraz, Suleyman ; Duran, Cihan ; Killi, Refik ; Ayanoglu, Omer ; Yuzer, Yildiray ; Tokat, Yaman. / Donor safety and remnant liver volume in living donor liver transplantation. In: Liver Transplantation. 2008 ; Vol. 14, No. 8. pp. 1174-1179.
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