Drug-induced linear immunoglobulin a bullous dermatosis mimicking Stevens-Johnson syndrome: A case report

Julie E. Cummings, Renee R. Snyder, Erica B. Kelly, Sharon S. Raimer

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Linear immunoglobulin A (IgA) bullous dermatosis (LABD) is a rare autoimmune disorder characterized by vesiculobullous mucocutaneous eruptions. LABD also has been reported as a drug-induced reaction. Idiopathic LABD and drug-induced LABD re clinically indistinguishable and can resemble bullous pemphigoid, dermatitis herpetiformis, or bullous erythema multiforme. LABD is diagnosed with direct immunofluorescence (DIF), and idiopathic LABD can be distinguished from drug-induced LABD with a careful medication history. We present the case of a 54-year-old man with drug-induced LABD after ingestion of rimantadine, zanamivir, and azithromycin for presumed influenza. The patient's bullous eruption resolved with discontinuation of the offending medications and treatment with prednisone and pentoxlfylline.

Original languageEnglish (US)
Pages (from-to)203-207
Number of pages5
JournalCutis
Volume79
Issue number3
StatePublished - Mar 1 2007

    Fingerprint

ASJC Scopus subject areas

  • Dermatology

Cite this

Cummings, J. E., Snyder, R. R., Kelly, E. B., & Raimer, S. S. (2007). Drug-induced linear immunoglobulin a bullous dermatosis mimicking Stevens-Johnson syndrome: A case report. Cutis, 79(3), 203-207.