Abstract
The development of antiviral drugs for Ebola and Marburg viruses has been slow. To date, beyond supportive care, no effective treatments, prophylactic measures, therapies, or vaccines are approved to treat or prevent filovirus infections. In this review, we examine the current treatments available to administer care for filovirus infection, the potential therapeutic targets that can be used for filovirus drug development, and the various drug targeting techniques used against filoviruses.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 191-200 |
| Number of pages | 10 |
| Journal | Infectious Disorders - Drug Targets |
| Volume | 9 |
| Issue number | 2 |
| State | Published - 2009 |
| Externally published | Yes |
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Keywords
- Drug targets
- Ebola virus
- Filoviridae
- Immunotherapy
- Marburg virus
- Pathogenesis
- Pathology
- Therapeutics
ASJC Scopus subject areas
- Molecular Medicine
- Microbiology (medical)
- Pharmacology
Cite this
Drug targets in infections with Ebola and Marburg viruses. / Gene, Olinger G.; Julia, Biggins E.; Vanessa, Melanson R.; Victoria, Wahl Jensen; Geisbert, Thomas; Lisa, Hensley E.
In: Infectious Disorders - Drug Targets, Vol. 9, No. 2, 2009, p. 191-200.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Drug targets in infections with Ebola and Marburg viruses
AU - Gene, Olinger G.
AU - Julia, Biggins E.
AU - Vanessa, Melanson R.
AU - Victoria, Wahl Jensen
AU - Geisbert, Thomas
AU - Lisa, Hensley E.
PY - 2009
Y1 - 2009
N2 - The development of antiviral drugs for Ebola and Marburg viruses has been slow. To date, beyond supportive care, no effective treatments, prophylactic measures, therapies, or vaccines are approved to treat or prevent filovirus infections. In this review, we examine the current treatments available to administer care for filovirus infection, the potential therapeutic targets that can be used for filovirus drug development, and the various drug targeting techniques used against filoviruses.
AB - The development of antiviral drugs for Ebola and Marburg viruses has been slow. To date, beyond supportive care, no effective treatments, prophylactic measures, therapies, or vaccines are approved to treat or prevent filovirus infections. In this review, we examine the current treatments available to administer care for filovirus infection, the potential therapeutic targets that can be used for filovirus drug development, and the various drug targeting techniques used against filoviruses.
KW - Drug targets
KW - Ebola virus
KW - Filoviridae
KW - Immunotherapy
KW - Marburg virus
KW - Pathogenesis
KW - Pathology
KW - Therapeutics
UR - http://www.scopus.com/inward/record.url?scp=67649203671&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67649203671&partnerID=8YFLogxK
M3 - Article
VL - 9
SP - 191
EP - 200
JO - Infectious Disorders - Drug Targets
JF - Infectious Disorders - Drug Targets
SN - 1871-5265
IS - 2
ER -