Keyphrases
Aldehyde Inhibitor
16%
Aldehydes
16%
Amino Acid Side Chains
16%
Anti-COVID-19 Drug
16%
Carbonyl Group
16%
Cathepsin L
100%
Causative Agents
16%
CoV-2
100%
COVID-19
33%
Cysteine Protease Inhibitor
16%
Dual Inhibitor
100%
Dual-acting
16%
Dual-target
33%
Dual-target Inhibitor
33%
EC50
16%
Glutamine
100%
Heteroatom
16%
Human Cathepsins
100%
Human Cells
16%
Hydrogen Bonding Interaction
16%
Hydrogen Bonds (H-bonds)
16%
Hydrophobic Amino Acids
16%
Inactivating mutation
16%
Indole
16%
Inhibition Constant
16%
Isostere
100%
Leucine
16%
Main Protease
16%
New Inhibitors
16%
Nirmatrelvir
16%
Partial Preferences
16%
Peptide Scaffold
16%
Peptidomimetic Inhibitors
16%
Peptidomimetics
33%
Pfizer
16%
Phenylalanine
16%
Protease
50%
Protein Maturation
16%
Pyridinyl
33%
Resistance Development
16%
SARS-CoV-2 3CL Protease
100%
Scaffold-based
16%
Target-based Approach
16%
Viral
16%
Viral Infection
16%
Viral Protease
33%
Viral Proteins
16%
X-ray Structure
16%
Pharmacology, Toxicology and Pharmaceutical Science
Alanine
42%
Aldehyde
28%
Amino Acid
28%
Carbonyl Derivative
14%
Cathepsin L
100%
Cysteine Proteinase
14%
EC50
14%
Glutamine
100%
Hydrogen Bond
14%
Indole
14%
Infection
14%
Leucine
14%
Nirmatrelvir
14%
Peptidomimetics
42%
Phenylalanine
14%
Preference
14%
Proteinase
100%
Proteinase Inhibitor
14%
SARS Coronavirus
100%
Viral Protein
14%
Virus Infection
14%