Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity

Keyphrases

• In Cancer 100%
• Amyloid Formation 100%
• Dual Role 100%
• Loss Function 100%
• Amyloid Fibrils 66%
• Amyloid-β Oligomers 66%
• Basal Cell Carcinoma 66%
• Alzheimer's Disease 33%
• Cancer Progression 33%
• Human Cancer 33%
• Protein Function 33%
• Tumor Protein p53 (TP53) 33%
• Genome Integrity 33%
• Human Cell Culture 33%
• Gain-of-function 33%
• Amyloidosis 33%
• Conformational Transition 33%
• Protein Conformation 33%
• Consensus Sequence 33%
• Phenotypic Outcome 33%
• Wild-type p53 33%
• Insoluble Aggregates 33%
• Amyloidogenic Diseases 33%
• Intracellular Aggregation 33%

Biochemistry, Genetics and Molecular Biology

• P53 100%
• Amyloid Protein 100%
• Conformation 15%
• Wild Type 7%
• Tumor Suppressor Protein 7%
• Protein Function 7%
• Conformational Change 7%
• Protein Conformation 7%
• Consensus Sequence 7%
• Human Cell Culture 7%

Immunology and Microbiology

• P53 100%
• Fibril 23%
• Conformation 15%
• Basal Cell 15%
• Wild Type 7%
• Human Cell Culture 7%
• Conformational Transition 7%
• Consensus Sequence 7%
• Protein Conformation 7%
• Protein Function 7%