Dynamic contrast-enhanced magnetic resonance imaging in Head and Neck Cancer: Differentiation of new H&N cancer, recurrent disease, and benign post-treatment changes

Mitsutomi Ishiyama; Todd Richards; Upendra Parvathaneni; Yoshimi Anzai

doi:10.1016/j.clinimag.2015.01.016

Dynamic contrast-enhanced magnetic resonance imaging in Head and Neck Cancer: Differentiation of new H&N cancer, recurrent disease, and benign post-treatment changes

Mitsutomi Ishiyama, Todd Richards, Upendra Parvathaneni, Yoshimi Anzai

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Purpose: To determine if dynamic contrast-enhanced (DCE)-magnetic resonance imaging (MRI) parameters such as permeability surface area (PS) and blood volume (BV) allow differentiating between new head and neck (HN) cancer, recurrent HN cancer, and post-treatment benign changes. Method: A total of 35 patients with newly diagnosed, recurrent, and benign post-treatment benign changes underwent DCE-MRI. PS and BV were calculated. Results: PS values of the lesion were 2.3×10⁴±5.8×10⁴ for the newly diagnosed cancer group, 3.3×10⁴±1.7×10⁴ for the recurrent cancer group, and 4.8×10⁴±8.1×10⁴ for the post-treatment benign change group (P = .031). Conclusion: Post-treatment benign changes in the HN region had significantly high permeability property than newly diagnosed or previously treated recurrent tumor.

Original language	English (US)
Pages (from-to)	566-570
Number of pages	5
Journal	Clinical Imaging
Volume	39
Issue number	4
DOIs	https://doi.org/10.1016/j.clinimag.2015.01.016
State	Published - 2015
Externally published	Yes

Keywords

Dynamic contrast-enhanced MRI
Head and neck cancer
Permeability surface area product

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.clinimag.2015.01.016

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@article{b5c65eef1f0b4418badcb4c3701d0f40,

title = "Dynamic contrast-enhanced magnetic resonance imaging in Head and Neck Cancer: Differentiation of new H&N cancer, recurrent disease, and benign post-treatment changes",

abstract = "Purpose: To determine if dynamic contrast-enhanced (DCE)-magnetic resonance imaging (MRI) parameters such as permeability surface area (PS) and blood volume (BV) allow differentiating between new head and neck (HN) cancer, recurrent HN cancer, and post-treatment benign changes. Method: A total of 35 patients with newly diagnosed, recurrent, and benign post-treatment benign changes underwent DCE-MRI. PS and BV were calculated. Results: PS values of the lesion were 2.3×104±5.8×104 for the newly diagnosed cancer group, 3.3×104±1.7×104 for the recurrent cancer group, and 4.8×104±8.1×104 for the post-treatment benign change group (P = .031). Conclusion: Post-treatment benign changes in the HN region had significantly high permeability property than newly diagnosed or previously treated recurrent tumor.",

keywords = "Dynamic contrast-enhanced MRI, Head and neck cancer, Permeability surface area product",

author = "Mitsutomi Ishiyama and Todd Richards and Upendra Parvathaneni and Yoshimi Anzai",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

doi = "10.1016/j.clinimag.2015.01.016",

language = "English (US)",

volume = "39",

pages = "566--570",

journal = "Clinical Imaging",

issn = "0899-7071",

publisher = "Elsevier Inc.",

number = "4",

}

TY - JOUR

T1 - Dynamic contrast-enhanced magnetic resonance imaging in Head and Neck Cancer

T2 - Differentiation of new H&N cancer, recurrent disease, and benign post-treatment changes

AU - Ishiyama, Mitsutomi

AU - Richards, Todd

AU - Parvathaneni, Upendra

AU - Anzai, Yoshimi

PY - 2015

Y1 - 2015

N2 - Purpose: To determine if dynamic contrast-enhanced (DCE)-magnetic resonance imaging (MRI) parameters such as permeability surface area (PS) and blood volume (BV) allow differentiating between new head and neck (HN) cancer, recurrent HN cancer, and post-treatment benign changes. Method: A total of 35 patients with newly diagnosed, recurrent, and benign post-treatment benign changes underwent DCE-MRI. PS and BV were calculated. Results: PS values of the lesion were 2.3×104±5.8×104 for the newly diagnosed cancer group, 3.3×104±1.7×104 for the recurrent cancer group, and 4.8×104±8.1×104 for the post-treatment benign change group (P = .031). Conclusion: Post-treatment benign changes in the HN region had significantly high permeability property than newly diagnosed or previously treated recurrent tumor.

AB - Purpose: To determine if dynamic contrast-enhanced (DCE)-magnetic resonance imaging (MRI) parameters such as permeability surface area (PS) and blood volume (BV) allow differentiating between new head and neck (HN) cancer, recurrent HN cancer, and post-treatment benign changes. Method: A total of 35 patients with newly diagnosed, recurrent, and benign post-treatment benign changes underwent DCE-MRI. PS and BV were calculated. Results: PS values of the lesion were 2.3×104±5.8×104 for the newly diagnosed cancer group, 3.3×104±1.7×104 for the recurrent cancer group, and 4.8×104±8.1×104 for the post-treatment benign change group (P = .031). Conclusion: Post-treatment benign changes in the HN region had significantly high permeability property than newly diagnosed or previously treated recurrent tumor.

KW - Dynamic contrast-enhanced MRI

KW - Head and neck cancer

KW - Permeability surface area product

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Dynamic contrast-enhanced magnetic resonance imaging in Head and Neck Cancer: Differentiation of new H&N cancer, recurrent disease, and benign post-treatment changes

Abstract

Keywords

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