Dynamic transmission of West Nile virus across the United States-Mexican border

Brian R. Mann, Allison R. McMullen, Hilda Guzman, Robert B. Tesh, Alan D.T. Barrett

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Confirmed clinical and veterinary cases of West Nile virus (WNV) infection in Mexico remain restricted to northern Mexico, supporting a unidirectional transmission model from the US into Mexico. Full-length genomic sequencing of nine WNV isolates obtained from Culex spp. mosquito pools in El Paso, Texas (n=7) and Cuidad Juarez, Mexico (n=2) from 2005 to 2010 demonstrates the co-circulation of three independent genetic groups, two of which belong to the southwestern (SW/WN03) genotype and the other to the North American (NA/WN02) genotype. These results indicate ongoing dynamic circulation of WNV between the United States and Mexico.

Original languageEnglish (US)
Pages (from-to)75-80
Number of pages6
JournalVirology
Volume436
Issue number1
DOIs
StatePublished - Feb 5 2013

Keywords

  • Flavivirus
  • Phylogenetics
  • Viral epidemiology
  • Viral evolution
  • West Nile virus

ASJC Scopus subject areas

  • Virology

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