Dynamic transmission of West Nile virus across the United States-Mexican border

Brian R. Mann; Allison R. McMullen; Hilda Guzman; Robert B. Tesh; Alan D.T. Barrett

doi:10.1016/j.virol.2012.10.023

Dynamic transmission of West Nile virus across the United States-Mexican border

Brian R. Mann, Allison R. McMullen, Hilda Guzman, Robert B. Tesh, Alan D.T. Barrett

Pathology

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Confirmed clinical and veterinary cases of West Nile virus (WNV) infection in Mexico remain restricted to northern Mexico, supporting a unidirectional transmission model from the US into Mexico. Full-length genomic sequencing of nine WNV isolates obtained from Culex spp. mosquito pools in El Paso, Texas (n=7) and Cuidad Juarez, Mexico (n=2) from 2005 to 2010 demonstrates the co-circulation of three independent genetic groups, two of which belong to the southwestern (SW/WN03) genotype and the other to the North American (NA/WN02) genotype. These results indicate ongoing dynamic circulation of WNV between the United States and Mexico.

Original language	English (US)
Pages (from-to)	75-80
Number of pages	6
Journal	Virology
Volume	436
Issue number	1
DOIs	https://doi.org/10.1016/j.virol.2012.10.023
State	Published - Feb 5 2013

Keywords

Flavivirus
Phylogenetics
Viral epidemiology
Viral evolution
West Nile virus

ASJC Scopus subject areas

Virology

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10.1016/j.virol.2012.10.023

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@article{cf6c3e4c3e30494285603b58aa1129fe,

title = "Dynamic transmission of West Nile virus across the United States-Mexican border",

abstract = "Confirmed clinical and veterinary cases of West Nile virus (WNV) infection in Mexico remain restricted to northern Mexico, supporting a unidirectional transmission model from the US into Mexico. Full-length genomic sequencing of nine WNV isolates obtained from Culex spp. mosquito pools in El Paso, Texas (n=7) and Cuidad Juarez, Mexico (n=2) from 2005 to 2010 demonstrates the co-circulation of three independent genetic groups, two of which belong to the southwestern (SW/WN03) genotype and the other to the North American (NA/WN02) genotype. These results indicate ongoing dynamic circulation of WNV between the United States and Mexico.",

keywords = "Flavivirus, Phylogenetics, Viral epidemiology, Viral evolution, West Nile virus",

author = "Mann, {Brian R.} and McMullen, {Allison R.} and Hilda Guzman and Tesh, {Robert B.} and Barrett, {Alan D.T.}",

note = "Funding Information: This work was supported in part by NIH grant AI 067847 and contract HHSN272201000040I/HHSN27200004/D04 . In addition, we thank Mary D'Anton and the Texas Department of State Health Services for the generous contribution of the WNV samples characterized in this study in addition to review of the final manuscript. We also thank Andrew Beck for helpful discussions and phylogenetic insight.",

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doi = "10.1016/j.virol.2012.10.023",

language = "English (US)",

volume = "436",

pages = "75--80",

journal = "Virology",

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T1 - Dynamic transmission of West Nile virus across the United States-Mexican border

AU - Mann, Brian R.

AU - McMullen, Allison R.

AU - Guzman, Hilda

AU - Tesh, Robert B.

AU - Barrett, Alan D.T.

N1 - Funding Information: This work was supported in part by NIH grant AI 067847 and contract HHSN272201000040I/HHSN27200004/D04 . In addition, we thank Mary D'Anton and the Texas Department of State Health Services for the generous contribution of the WNV samples characterized in this study in addition to review of the final manuscript. We also thank Andrew Beck for helpful discussions and phylogenetic insight.

PY - 2013/2/5

Y1 - 2013/2/5

N2 - Confirmed clinical and veterinary cases of West Nile virus (WNV) infection in Mexico remain restricted to northern Mexico, supporting a unidirectional transmission model from the US into Mexico. Full-length genomic sequencing of nine WNV isolates obtained from Culex spp. mosquito pools in El Paso, Texas (n=7) and Cuidad Juarez, Mexico (n=2) from 2005 to 2010 demonstrates the co-circulation of three independent genetic groups, two of which belong to the southwestern (SW/WN03) genotype and the other to the North American (NA/WN02) genotype. These results indicate ongoing dynamic circulation of WNV between the United States and Mexico.

AB - Confirmed clinical and veterinary cases of West Nile virus (WNV) infection in Mexico remain restricted to northern Mexico, supporting a unidirectional transmission model from the US into Mexico. Full-length genomic sequencing of nine WNV isolates obtained from Culex spp. mosquito pools in El Paso, Texas (n=7) and Cuidad Juarez, Mexico (n=2) from 2005 to 2010 demonstrates the co-circulation of three independent genetic groups, two of which belong to the southwestern (SW/WN03) genotype and the other to the North American (NA/WN02) genotype. These results indicate ongoing dynamic circulation of WNV between the United States and Mexico.

KW - Flavivirus

KW - Phylogenetics

KW - Viral epidemiology

KW - Viral evolution

KW - West Nile virus

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Dynamic transmission of West Nile virus across the United States-Mexican border

Abstract

Keywords

ASJC Scopus subject areas

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