Dynamics-derived insights into complex formation between the CXCL8 monomer and CXCR1 N-terminal domain: An NMR study

Keyphrases

• CXCR1 100%
• N-terminal Domain 100%
• Nuclear Magnetic Resonance 100%
• Complex Formation 100%
• CXCL8 100%
• Magnetic Resonance Techniques 100%
• Bound States 62%
• Free State 25%
• G Protein-coupled Receptor 12%
• Chemokines 12%
• Neutrophils 12%
• High Affinity 12%
• Interleukin-8 12%
• Receptor Activation 12%
• Dynamic Properties 12%
• Transmembrane 12%
• N-terminal Loop 12%
• Isothermal Titration Calorimetry 12%
• 15N Relaxation 12%
• Complex Role 12%
• Main Chain 12%
• Picosecond 12%
• Slow Dynamics 12%
• Higher-order Parameters 12%
• Entropic Factors 12%

Biochemistry, Genetics and Molecular Biology

• Dynamics 100%
• N-Terminus 100%
• Complex Formation 100%
• G Protein Coupled Receptor 16%
• Chemokine 16%
• Interleukin 8 16%
• Isothermal Titration Calorimetry 16%
• Interleukin 8 Receptor, Alpha 16%
• Nuclear Magnetic Resonance Relaxation 16%