Early calcific stenosis of aortic and mitral Ionescu-Shiley valves in a patient with bioprosthetic infection

E. H. Williams, Vincent Conti, A. Nishimura

Research output: Contribution to journalArticle

9 Scopus citations


The clinical course of a patient with bioprosthetic failure of aortic and mitral Ionescu-Shiley valves (which contain bovine pericardial leaflets) is presented. Failure occurred in less than 4 months and was due to infection that resulted in calcification and severe stenoses. On examination of tissue specimens under light and electron microscopes, the pathologic process was seen to be similar to that occurring with infected porcine prostheses.

Original languageEnglish (US)
Pages (from-to)391-397
Number of pages7
JournalJournal of Thoracic and Cardiovascular Surgery
Issue number3
StatePublished - 1981


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

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