Early diagnosis of rickettsioses by electrochemiluminscence

Gary Wen, Jere W. McBride, Xiaofeng Zhang, Juan P. Olano

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The diagnosis of acute rickettsioses during the acute phase of the disease is challenging. We present preliminary evidence that antigen-capture using streptavidin-coated magnetic beads with biotinylated smti-rickettsia typhi rabbit polyclonal antibodies followed by electrochemiluminescent detection with ruthenylated antibodies of the same specificity could be used for the diagnosis of rickettsial diseases in the acute phase.

Original languageEnglish (US)
Title of host publicationCentury of Rickettsiology; Emerging, Reemerging Rickettsioses, Molecular Diagnostics. amd Emerging Veterinary Rickettsioses
PublisherBlackwell Publishing Inc.
Pages590-594
Number of pages5
ISBN (Print)1573316393, 9781573316392
DOIs
StatePublished - Oct 2006

Publication series

NameAnnals of the New York Academy of Sciences
Volume1078
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632

Keywords

  • Electrochemiluminescence
  • Rickettsia typhi
  • Rickettsioses
  • Ruthenium (II) tris-bipyridine
  • Tripropylamine

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

Fingerprint Dive into the research topics of 'Early diagnosis of rickettsioses by electrochemiluminscence'. Together they form a unique fingerprint.

  • Cite this

    Wen, G., McBride, J. W., Zhang, X., & Olano, J. P. (2006). Early diagnosis of rickettsioses by electrochemiluminscence. In Century of Rickettsiology; Emerging, Reemerging Rickettsioses, Molecular Diagnostics. amd Emerging Veterinary Rickettsioses (pp. 590-594). (Annals of the New York Academy of Sciences; Vol. 1078). Blackwell Publishing Inc.. https://doi.org/10.1196/annals.1374.118