Early diagnosis of rickettsioses by electrochemiluminscence

Gary Wen, Jere McBride, Xiaofeng Zhang, Juan Olano

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The diagnosis of acute rickettsioses during the acute phase of the disease is challenging. We present preliminary evidence that antigen-capture using streptavidin-coated magnetic beads with biotinylated smti-rickettsia typhi rabbit polyclonal antibodies followed by electrochemiluminescent detection with ruthenylated antibodies of the same specificity could be used for the diagnosis of rickettsial diseases in the acute phase.

Original languageEnglish (US)
Title of host publicationAnnals of the New York Academy of Sciences
Pages590-594
Number of pages5
Volume1078
DOIs
StatePublished - Oct 2006

Publication series

NameAnnals of the New York Academy of Sciences
Volume1078
ISSN (Print)00778923
ISSN (Electronic)17496632

Fingerprint

Acute Disease
Early Diagnosis
Rickettsia typhi
Antibody Specificity
Streptavidin
Antibodies
Rabbits
Antigens

Keywords

  • Electrochemiluminescence
  • Rickettsia typhi
  • Rickettsioses
  • Ruthenium (II) tris-bipyridine
  • Tripropylamine

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Wen, G., McBride, J., Zhang, X., & Olano, J. (2006). Early diagnosis of rickettsioses by electrochemiluminscence. In Annals of the New York Academy of Sciences (Vol. 1078, pp. 590-594). (Annals of the New York Academy of Sciences; Vol. 1078). https://doi.org/10.1196/annals.1374.118

Early diagnosis of rickettsioses by electrochemiluminscence. / Wen, Gary; McBride, Jere; Zhang, Xiaofeng; Olano, Juan.

Annals of the New York Academy of Sciences. Vol. 1078 2006. p. 590-594 (Annals of the New York Academy of Sciences; Vol. 1078).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wen, G, McBride, J, Zhang, X & Olano, J 2006, Early diagnosis of rickettsioses by electrochemiluminscence. in Annals of the New York Academy of Sciences. vol. 1078, Annals of the New York Academy of Sciences, vol. 1078, pp. 590-594. https://doi.org/10.1196/annals.1374.118
Wen G, McBride J, Zhang X, Olano J. Early diagnosis of rickettsioses by electrochemiluminscence. In Annals of the New York Academy of Sciences. Vol. 1078. 2006. p. 590-594. (Annals of the New York Academy of Sciences). https://doi.org/10.1196/annals.1374.118
Wen, Gary ; McBride, Jere ; Zhang, Xiaofeng ; Olano, Juan. / Early diagnosis of rickettsioses by electrochemiluminscence. Annals of the New York Academy of Sciences. Vol. 1078 2006. pp. 590-594 (Annals of the New York Academy of Sciences).
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