Early onset scoliosis

Modern treatment and results

John E. Tis, Lawrence I. Karlin, Behrooz A. Akbarnia, Laurel C. Blakemore, George H. Thompson, Richard E. McCarthy, Carlos A. Tello, Michael J. Mendelow, Edward Southern

Research output: Contribution to journalReview article

54 Citations (Scopus)

Abstract

BACKGROUND: Early onset scoliosis (EOS) is a potentially fatal, challenging group of diseases the management of which has markedly changed in the last decade. The purpose of this review is to provide the reader with a brief description of each of these new therapeutic modalities, their indications for use, and early clinical results. METHODS: A systematic review of peer-reviewed publications and abstracts related to the treatment of EOS in the last decade was carried out and synthesized into a review of modern treatment methods. RESULTS: Recent advances in techniques and understanding of preserving the thoracic space have improved the morbidity and mortality of children with progressive EOS. Derotational casting may be used in younger patients with curves between 25 and 60 degrees. The vertical expandable prosthetic titanium rib is best suited for patients with thoracic insufficiency syndrome. Single or dual growing rods may be used alone or in combination with vertical expandable prosthetic titanium rib to treat patients with progressive EOS who are not candidates for casting. Shilla technique is an alternative to growing rods that avoids the morbidity of repeated lengthenings but is not as well proven as the techniques described above. Other methods such as automatic growing rods and growth modulation techniques are still investigational, and their role needs to be defined after further study. CONCLUSIONS: Recent advances have improved the treatment of children with EOS. Treatment continues to be challenging with complication rates higher than treatment of idiopathic scoliosis. LEVEL OF EVIDENCE: Level V.

Original languageEnglish (US)
Pages (from-to)647-657
Number of pages11
JournalJournal of Pediatric Orthopaedics
Volume32
Issue number7
DOIs
StatePublished - Oct 1 2012
Externally publishedYes

Fingerprint

Scoliosis
Ribs
Titanium
Thorax
Therapeutics
Morbidity
Child Mortality
Peer Review
Disease Management
Publications
Growth

Keywords

  • derotation body cast
  • early onset scoliosis
  • growing rods
  • hybrid growing rods
  • Shilla
  • VEPTR
  • vertebral stapling

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Orthopedics and Sports Medicine

Cite this

Tis, J. E., Karlin, L. I., Akbarnia, B. A., Blakemore, L. C., Thompson, G. H., McCarthy, R. E., ... Southern, E. (2012). Early onset scoliosis: Modern treatment and results. Journal of Pediatric Orthopaedics, 32(7), 647-657. https://doi.org/10.1097/BPO.0b013e3182694f18

Early onset scoliosis : Modern treatment and results. / Tis, John E.; Karlin, Lawrence I.; Akbarnia, Behrooz A.; Blakemore, Laurel C.; Thompson, George H.; McCarthy, Richard E.; Tello, Carlos A.; Mendelow, Michael J.; Southern, Edward.

In: Journal of Pediatric Orthopaedics, Vol. 32, No. 7, 01.10.2012, p. 647-657.

Research output: Contribution to journalReview article

Tis, JE, Karlin, LI, Akbarnia, BA, Blakemore, LC, Thompson, GH, McCarthy, RE, Tello, CA, Mendelow, MJ & Southern, E 2012, 'Early onset scoliosis: Modern treatment and results', Journal of Pediatric Orthopaedics, vol. 32, no. 7, pp. 647-657. https://doi.org/10.1097/BPO.0b013e3182694f18
Tis JE, Karlin LI, Akbarnia BA, Blakemore LC, Thompson GH, McCarthy RE et al. Early onset scoliosis: Modern treatment and results. Journal of Pediatric Orthopaedics. 2012 Oct 1;32(7):647-657. https://doi.org/10.1097/BPO.0b013e3182694f18
Tis, John E. ; Karlin, Lawrence I. ; Akbarnia, Behrooz A. ; Blakemore, Laurel C. ; Thompson, George H. ; McCarthy, Richard E. ; Tello, Carlos A. ; Mendelow, Michael J. ; Southern, Edward. / Early onset scoliosis : Modern treatment and results. In: Journal of Pediatric Orthopaedics. 2012 ; Vol. 32, No. 7. pp. 647-657.
@article{25b7a37842e8489b858b3334f06916b7,
title = "Early onset scoliosis: Modern treatment and results",
abstract = "BACKGROUND: Early onset scoliosis (EOS) is a potentially fatal, challenging group of diseases the management of which has markedly changed in the last decade. The purpose of this review is to provide the reader with a brief description of each of these new therapeutic modalities, their indications for use, and early clinical results. METHODS: A systematic review of peer-reviewed publications and abstracts related to the treatment of EOS in the last decade was carried out and synthesized into a review of modern treatment methods. RESULTS: Recent advances in techniques and understanding of preserving the thoracic space have improved the morbidity and mortality of children with progressive EOS. Derotational casting may be used in younger patients with curves between 25 and 60 degrees. The vertical expandable prosthetic titanium rib is best suited for patients with thoracic insufficiency syndrome. Single or dual growing rods may be used alone or in combination with vertical expandable prosthetic titanium rib to treat patients with progressive EOS who are not candidates for casting. Shilla technique is an alternative to growing rods that avoids the morbidity of repeated lengthenings but is not as well proven as the techniques described above. Other methods such as automatic growing rods and growth modulation techniques are still investigational, and their role needs to be defined after further study. CONCLUSIONS: Recent advances have improved the treatment of children with EOS. Treatment continues to be challenging with complication rates higher than treatment of idiopathic scoliosis. LEVEL OF EVIDENCE: Level V.",
keywords = "derotation body cast, early onset scoliosis, growing rods, hybrid growing rods, Shilla, VEPTR, vertebral stapling",
author = "Tis, {John E.} and Karlin, {Lawrence I.} and Akbarnia, {Behrooz A.} and Blakemore, {Laurel C.} and Thompson, {George H.} and McCarthy, {Richard E.} and Tello, {Carlos A.} and Mendelow, {Michael J.} and Edward Southern",
year = "2012",
month = "10",
day = "1",
doi = "10.1097/BPO.0b013e3182694f18",
language = "English (US)",
volume = "32",
pages = "647--657",
journal = "Journal of Pediatric Orthopaedics",
issn = "0271-6798",
publisher = "Lippincott Williams and Wilkins",
number = "7",

}

TY - JOUR

T1 - Early onset scoliosis

T2 - Modern treatment and results

AU - Tis, John E.

AU - Karlin, Lawrence I.

AU - Akbarnia, Behrooz A.

AU - Blakemore, Laurel C.

AU - Thompson, George H.

AU - McCarthy, Richard E.

AU - Tello, Carlos A.

AU - Mendelow, Michael J.

AU - Southern, Edward

PY - 2012/10/1

Y1 - 2012/10/1

N2 - BACKGROUND: Early onset scoliosis (EOS) is a potentially fatal, challenging group of diseases the management of which has markedly changed in the last decade. The purpose of this review is to provide the reader with a brief description of each of these new therapeutic modalities, their indications for use, and early clinical results. METHODS: A systematic review of peer-reviewed publications and abstracts related to the treatment of EOS in the last decade was carried out and synthesized into a review of modern treatment methods. RESULTS: Recent advances in techniques and understanding of preserving the thoracic space have improved the morbidity and mortality of children with progressive EOS. Derotational casting may be used in younger patients with curves between 25 and 60 degrees. The vertical expandable prosthetic titanium rib is best suited for patients with thoracic insufficiency syndrome. Single or dual growing rods may be used alone or in combination with vertical expandable prosthetic titanium rib to treat patients with progressive EOS who are not candidates for casting. Shilla technique is an alternative to growing rods that avoids the morbidity of repeated lengthenings but is not as well proven as the techniques described above. Other methods such as automatic growing rods and growth modulation techniques are still investigational, and their role needs to be defined after further study. CONCLUSIONS: Recent advances have improved the treatment of children with EOS. Treatment continues to be challenging with complication rates higher than treatment of idiopathic scoliosis. LEVEL OF EVIDENCE: Level V.

AB - BACKGROUND: Early onset scoliosis (EOS) is a potentially fatal, challenging group of diseases the management of which has markedly changed in the last decade. The purpose of this review is to provide the reader with a brief description of each of these new therapeutic modalities, their indications for use, and early clinical results. METHODS: A systematic review of peer-reviewed publications and abstracts related to the treatment of EOS in the last decade was carried out and synthesized into a review of modern treatment methods. RESULTS: Recent advances in techniques and understanding of preserving the thoracic space have improved the morbidity and mortality of children with progressive EOS. Derotational casting may be used in younger patients with curves between 25 and 60 degrees. The vertical expandable prosthetic titanium rib is best suited for patients with thoracic insufficiency syndrome. Single or dual growing rods may be used alone or in combination with vertical expandable prosthetic titanium rib to treat patients with progressive EOS who are not candidates for casting. Shilla technique is an alternative to growing rods that avoids the morbidity of repeated lengthenings but is not as well proven as the techniques described above. Other methods such as automatic growing rods and growth modulation techniques are still investigational, and their role needs to be defined after further study. CONCLUSIONS: Recent advances have improved the treatment of children with EOS. Treatment continues to be challenging with complication rates higher than treatment of idiopathic scoliosis. LEVEL OF EVIDENCE: Level V.

KW - derotation body cast

KW - early onset scoliosis

KW - growing rods

KW - hybrid growing rods

KW - Shilla

KW - VEPTR

KW - vertebral stapling

UR - http://www.scopus.com/inward/record.url?scp=84866249800&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84866249800&partnerID=8YFLogxK

U2 - 10.1097/BPO.0b013e3182694f18

DO - 10.1097/BPO.0b013e3182694f18

M3 - Review article

VL - 32

SP - 647

EP - 657

JO - Journal of Pediatric Orthopaedics

JF - Journal of Pediatric Orthopaedics

SN - 0271-6798

IS - 7

ER -