Early use of allograft skin

Are 3-day microbiologic cultures safe?

Benita W. Britton-Byrd, James P. Lynch, Stephen Williamson, Robert L. McCauley

    Research output: Contribution to journalArticle

    5 Citations (Scopus)

    Abstract

    BACKGROUND: Under the guidance of the American Association of Tissue Banks and the Food and Drug Administration, the use of allograft skin is safer than ever. In addition to the donor selection process and serology studies, current practice is to wait until 7 days of negative microbiologic cultures are completed before use. However, we have used 3 days of negative cultures in special cases as needed for clinical use. But how safe is this practice? METHODS: Between 2002 and 2003, 735 allograft skin donors were authorized for exceptional release. Exceptional release forms were signed by surgeons to document knowledge of the 3-day microbiologic cultures. RESULTS: Only three donors were recalled for positive cultures. The recall rate was 0.41%. CONCLUSIONS: The use of 3-day microbiologic cultures is 99.59% safe. Thus, the early use of allograft skin does not increase the chances of microbiologic contamination to patients.

    Original languageEnglish (US)
    Pages (from-to)816-818
    Number of pages3
    JournalJournal of Trauma - Injury, Infection and Critical Care
    Volume64
    Issue number3
    DOIs
    StatePublished - Mar 2008

    Fingerprint

    Allografts
    Skin
    Tissue Donors
    Tissue Banks
    Donor Selection
    Serology
    United States Food and Drug Administration
    Surgeons

    Keywords

    • Allograft skin
    • Burns
    • Microbiology cultures

    ASJC Scopus subject areas

    • Surgery

    Cite this

    Early use of allograft skin : Are 3-day microbiologic cultures safe? / Britton-Byrd, Benita W.; Lynch, James P.; Williamson, Stephen; McCauley, Robert L.

    In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 64, No. 3, 03.2008, p. 816-818.

    Research output: Contribution to journalArticle

    Britton-Byrd, Benita W. ; Lynch, James P. ; Williamson, Stephen ; McCauley, Robert L. / Early use of allograft skin : Are 3-day microbiologic cultures safe?. In: Journal of Trauma - Injury, Infection and Critical Care. 2008 ; Vol. 64, No. 3. pp. 816-818.
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