Effect of blocking the CXCL9/10-CXCR3 chemokine system in the outcome of endothelial-target rickettsial infections

Keyphrases

• Rickettsial Infection 100%
• Rickettsia 100%
• CXCR3 Chemokines 100%
• CXCL9 100%
• Chemokine System 100%
• T Cells 50%
• CXCL10 50%
• Vasculature 25%
• Effector Mechanisms 25%
• T-cell Mediated 25%
• Chemokines 25%
• Endothelial Cells 25%
• Rocky Mountain Spotted Fever 25%
• Intracellular Bacteria 25%
• Systemic Infection 25%
• Rickettsial 25%
• Endothelium 25%
• Cellular Targets 25%
• Boutonneuse Fever 25%
• Intercellular Adhesion molecule-1 (ICAM-1) 25%
• Vascular Cell Adhesion molecule-1 (VCAM-1) 25%
• Antibody-mediated Neutralization 25%
• Bacterial Load 25%
• CXCR3 25%
• Gene Knockout 25%
• Inflammatory Phenotype 25%
• Effects on Survival 25%
• Expression Study 25%
• CXCR3 Ligands 25%

Immunology and Microbiology

• Chemokine 100%
• Rickettsia 100%
• Infectious Disease 100%
• CXCR3 100%
• CXCL9 100%
• Infection 100%
• T Cell 75%
• CXCL10 50%
• Vascularization 25%
• Intracellular Bacterium 25%
• Neutralization 25%
• VCAM-1 25%
• Bacterial Load 25%
• Gene Knockout 25%
• Gene Targeting 25%
• Intercellular Adhesion Molecule 1 25%
• Endothelium 25%
• Endothelial Cells 25%