Effect of Bombesin and Gastrin-Releasing Peptide on the Release of Gastric Inhibitory Polypeptide and Insulin in Rats

George H. Greeley, Alan Spannagel, John Trowbridge, James C. Thompson

    Research output: Contribution to journalArticle

    6 Scopus citations

    Abstract

    The objective of this study was to determine whether bombesin- or gastrin-releasing peptide-induced release of insulin occurs before or after the release of gastric inhibitory polypeptide (GIP) in rats. The present results demonstrate that GIP release occurs before insulin release and suggest that bombesin-like peptides and GIP interact to stimulate insulin secretion.

    Original languageEnglish (US)
    Pages (from-to)540-542
    Number of pages3
    JournalProceedings of the Society for Experimental Biology and Medicine
    Volume182
    Issue number4
    DOIs
    StatePublished - Sep 1986

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

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