Effect of coagulation on laser light distribution in myocardial tissue

Ramtin Agah, Devang Sheth, Massoud Motamedi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The changes in total reflection and transmission of porcine myocardium due to thermal coagulation were measured during tissue heating in a temperature-controlled water bath, at different temperature ranging between 54°-63°C. At 633 nm, the measurements yield a picture of continuous decrease in transmission and a peak with a subsequent fall (approximately 10% from the peak) in reflection measurements of the tissue during coagulation process. Utilizing these measurements and an inverse solution to the radiative transfer equation, the optical properties of tissue, absorption, μ a, and effective scattering, μ′ s= μ s(l-g) were calculated. A one-dimensional diffusion approximation was used to demonstrate the effects of thermally induced changes in the optical properties of tissue on light distribution in tissue. The pattern of changes in μ a and μ′ s seen to indicate that several simultaneous rate processes may be responsible for tissue coagulation. A postulate is put forward to use one such rate process to characterize threshold thermal damage to porcine myocardium and the accompanying protein denaturation.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsGeorge S. Abela, Abraham Katzir
PublisherPubl by Int Soc for Optical Engineering
Pages172-179
Number of pages8
Volume1425
StatePublished - 1991
Externally publishedYes
EventProceedings of Diagnostic and Therapeutic Cardiovascular Interventions - Los Angeles, CA, USA
Duration: Jan 20 1991Jan 22 1991

Other

OtherProceedings of Diagnostic and Therapeutic Cardiovascular Interventions
CityLos Angeles, CA, USA
Period1/20/911/22/91

Fingerprint

coagulation
Coagulation
Tissue
Lasers
lasers
myocardium
Optical properties
optical properties
Denaturation
biopolymer denaturation
Radiative transfer
axioms
radiative transfer
baths
Scattering
damage
Proteins
Heating
Temperature
heating

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Agah, R., Sheth, D., & Motamedi, M. (1991). Effect of coagulation on laser light distribution in myocardial tissue. In G. S. Abela, & A. Katzir (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 1425, pp. 172-179). Publ by Int Soc for Optical Engineering.

Effect of coagulation on laser light distribution in myocardial tissue. / Agah, Ramtin; Sheth, Devang; Motamedi, Massoud.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / George S. Abela; Abraham Katzir. Vol. 1425 Publ by Int Soc for Optical Engineering, 1991. p. 172-179.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Agah, R, Sheth, D & Motamedi, M 1991, Effect of coagulation on laser light distribution in myocardial tissue. in GS Abela & A Katzir (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 1425, Publ by Int Soc for Optical Engineering, pp. 172-179, Proceedings of Diagnostic and Therapeutic Cardiovascular Interventions, Los Angeles, CA, USA, 1/20/91.
Agah R, Sheth D, Motamedi M. Effect of coagulation on laser light distribution in myocardial tissue. In Abela GS, Katzir A, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 1425. Publ by Int Soc for Optical Engineering. 1991. p. 172-179
Agah, Ramtin ; Sheth, Devang ; Motamedi, Massoud. / Effect of coagulation on laser light distribution in myocardial tissue. Proceedings of SPIE - The International Society for Optical Engineering. editor / George S. Abela ; Abraham Katzir. Vol. 1425 Publ by Int Soc for Optical Engineering, 1991. pp. 172-179
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