Effect of hemodialysis on left ventricular performance: Analysis of echocardiographic subsets1

Bard R. Madsen, Martin A. Alpert, Richard B. Whiting, John Van Stone, Masood Ahmad, Diana L. Kelly

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

To assess the effect of hemodialysis on left ventricular performance, we performed M-mode echocardiography on 31 patients with end-stagc renal disease prior to and immediately following 4-hour chronic maintenance hemodialysis. Overall, hemodialysis produced a significant increase in mean heart rate and the mean velocity of circumferential fiber shortening (mean Vcf), a significant decrease in mean stroke index and no significant change in mean cardiac index. Hemodialysis resulted in a significant increase in mean Vcf in the subset of patients with reduced mean Vcf prior to dialysis, but produced no significant change in mean Vcf in the group with normal predialysis mean Vcf. Hemodialysis resulted in a significant increase in mean Vcf in the subset of patients with normal left ventricular end-diastolic volume prior to dialysis, but produced no significant change in mean Vcf in the group with increased predialysis left ventricular end-diastolic volume. The presence of left ventricular hypertrophy appeared to blunt the expected increase in mean Vcf in the group with reduced mean Vcf prior to hemodialysis. These results suggest that predialysis left ventricular volume, wall thickness and contractility are important determinants of the effect of hemodialysis on left ventricular performance.

Original languageEnglish (US)
Pages (from-to)86-91
Number of pages6
JournalAmerican journal of nephrology
Volume4
Issue number2
DOIs
StatePublished - Jan 1 1984
Externally publishedYes

Keywords

  • Hemodialysis
  • Left ventricular end-diastolic volume
  • Left ventricular hypertrophy
  • M-mode echocardiography
  • Mean velocity of circumferential fiber shortening

ASJC Scopus subject areas

  • Nephrology

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