Effect of high-intensity interval exercise on basal triglyceride metabolism in non-obese men

Elena Bellou, Faidon Magkos, Tonia Kouka, Eirini Bouchalaki, Dimitra Sklaveniti, Maria Maraki, Yiannis E. Tsekouras, Demosthenes B. Panagiotakos, Stavros A. Kavouras, Labros S. Sidossis

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A single bout of high-intensity interval aerobic exercise has been shown to produce the same or greater metabolic benefits as continuous endurance exercise with considerably less energy expenditure, but whether this applies to very low density lipoprotein (VLDL) metabolism is not known. We sought to examine the effect of a single bout of high-intensity interval aerobic exercise on basal VLDL-triglyceride (TG) kinetics 14 and 48 h after exercise cessation to determine the acute and time-dependent effects of this type of exercise on VLDL-TG metabolism. Eight healthy sedentary men (age, 23.6 ± 6.1 years; body mass index, 23.1 ± 2.2 kg·m-2, peak oxygen consumption (V̇O2peak), 36.3 ± 5.5 mL·kg-1·min-1) participated in three stable isotopically labeled tracer infusion studies: (i) 14 h and (ii) 48 h after a single bout of high-intensity aerobic interval exercise (60% and 90% of V̇O2peak in 4 min intervals for a total of 32 min; gross energy expenditure ~500 kcal) and (iii) after an equivalent period of rest, in random order. Fasting plasma VLDL-TG concentration was 20% lower at 14 h (P = 0.046) but not at 48 h (P = 1.000) after exercise compared with the resting trial. VLDL-TG plasma clearance rate increased by 21% at 14 h (P < 0.001) but not at 48 h (P = 0.299) after exercise compared with rest, whereas hepatic VLDL-TG secretion rate was not different from rest at any time point after exercise. We conclude that high-intensity interval exercise reduces fasting plasma VLDL-TG concentrations in non-obese men the next day by augmenting VLDL-TG clearance, just like a single bout of continuous endurance exercise. This effect is short-lived and abolished by 48 h after exercise.

Original languageEnglish (US)
Pages (from-to)823-829
Number of pages7
JournalApplied Physiology, Nutrition and Metabolism
Volume38
Issue number8
DOIs
StatePublished - Jul 2013

Fingerprint

Basal Metabolism
Triglycerides
Exercise
Energy Metabolism
Fasting
VLDL Lipoproteins
very low density lipoprotein triglyceride
Oxygen Consumption
Body Mass Index

Keywords

  • Aerobic
  • Hypotriglyceridemia
  • Kinetics
  • Lean
  • Physical activity
  • Triacylglycerol

ASJC Scopus subject areas

  • Physiology
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics
  • Physiology (medical)

Cite this

Bellou, E., Magkos, F., Kouka, T., Bouchalaki, E., Sklaveniti, D., Maraki, M., ... Sidossis, L. S. (2013). Effect of high-intensity interval exercise on basal triglyceride metabolism in non-obese men. Applied Physiology, Nutrition and Metabolism, 38(8), 823-829. https://doi.org/10.1139/apnm-2012-0468

Effect of high-intensity interval exercise on basal triglyceride metabolism in non-obese men. / Bellou, Elena; Magkos, Faidon; Kouka, Tonia; Bouchalaki, Eirini; Sklaveniti, Dimitra; Maraki, Maria; Tsekouras, Yiannis E.; Panagiotakos, Demosthenes B.; Kavouras, Stavros A.; Sidossis, Labros S.

In: Applied Physiology, Nutrition and Metabolism, Vol. 38, No. 8, 07.2013, p. 823-829.

Research output: Contribution to journalArticle

Bellou, E, Magkos, F, Kouka, T, Bouchalaki, E, Sklaveniti, D, Maraki, M, Tsekouras, YE, Panagiotakos, DB, Kavouras, SA & Sidossis, LS 2013, 'Effect of high-intensity interval exercise on basal triglyceride metabolism in non-obese men', Applied Physiology, Nutrition and Metabolism, vol. 38, no. 8, pp. 823-829. https://doi.org/10.1139/apnm-2012-0468
Bellou, Elena ; Magkos, Faidon ; Kouka, Tonia ; Bouchalaki, Eirini ; Sklaveniti, Dimitra ; Maraki, Maria ; Tsekouras, Yiannis E. ; Panagiotakos, Demosthenes B. ; Kavouras, Stavros A. ; Sidossis, Labros S. / Effect of high-intensity interval exercise on basal triglyceride metabolism in non-obese men. In: Applied Physiology, Nutrition and Metabolism. 2013 ; Vol. 38, No. 8. pp. 823-829.
@article{f7490923efb5436686ecbc45af5eaa5d,
title = "Effect of high-intensity interval exercise on basal triglyceride metabolism in non-obese men",
abstract = "A single bout of high-intensity interval aerobic exercise has been shown to produce the same or greater metabolic benefits as continuous endurance exercise with considerably less energy expenditure, but whether this applies to very low density lipoprotein (VLDL) metabolism is not known. We sought to examine the effect of a single bout of high-intensity interval aerobic exercise on basal VLDL-triglyceride (TG) kinetics 14 and 48 h after exercise cessation to determine the acute and time-dependent effects of this type of exercise on VLDL-TG metabolism. Eight healthy sedentary men (age, 23.6 ± 6.1 years; body mass index, 23.1 ± 2.2 kg·m-2, peak oxygen consumption (V̇O2peak), 36.3 ± 5.5 mL·kg-1·min-1) participated in three stable isotopically labeled tracer infusion studies: (i) 14 h and (ii) 48 h after a single bout of high-intensity aerobic interval exercise (60{\%} and 90{\%} of V̇O2peak in 4 min intervals for a total of 32 min; gross energy expenditure ~500 kcal) and (iii) after an equivalent period of rest, in random order. Fasting plasma VLDL-TG concentration was 20{\%} lower at 14 h (P = 0.046) but not at 48 h (P = 1.000) after exercise compared with the resting trial. VLDL-TG plasma clearance rate increased by 21{\%} at 14 h (P < 0.001) but not at 48 h (P = 0.299) after exercise compared with rest, whereas hepatic VLDL-TG secretion rate was not different from rest at any time point after exercise. We conclude that high-intensity interval exercise reduces fasting plasma VLDL-TG concentrations in non-obese men the next day by augmenting VLDL-TG clearance, just like a single bout of continuous endurance exercise. This effect is short-lived and abolished by 48 h after exercise.",
keywords = "Aerobic, Hypotriglyceridemia, Kinetics, Lean, Physical activity, Triacylglycerol",
author = "Elena Bellou and Faidon Magkos and Tonia Kouka and Eirini Bouchalaki and Dimitra Sklaveniti and Maria Maraki and Tsekouras, {Yiannis E.} and Panagiotakos, {Demosthenes B.} and Kavouras, {Stavros A.} and Sidossis, {Labros S.}",
year = "2013",
month = "7",
doi = "10.1139/apnm-2012-0468",
language = "English (US)",
volume = "38",
pages = "823--829",
journal = "Applied Physiology, Nutrition and Metabolism",
issn = "1715-5312",
publisher = "National Research Council of Canada",
number = "8",

}

TY - JOUR

T1 - Effect of high-intensity interval exercise on basal triglyceride metabolism in non-obese men

AU - Bellou, Elena

AU - Magkos, Faidon

AU - Kouka, Tonia

AU - Bouchalaki, Eirini

AU - Sklaveniti, Dimitra

AU - Maraki, Maria

AU - Tsekouras, Yiannis E.

AU - Panagiotakos, Demosthenes B.

AU - Kavouras, Stavros A.

AU - Sidossis, Labros S.

PY - 2013/7

Y1 - 2013/7

N2 - A single bout of high-intensity interval aerobic exercise has been shown to produce the same or greater metabolic benefits as continuous endurance exercise with considerably less energy expenditure, but whether this applies to very low density lipoprotein (VLDL) metabolism is not known. We sought to examine the effect of a single bout of high-intensity interval aerobic exercise on basal VLDL-triglyceride (TG) kinetics 14 and 48 h after exercise cessation to determine the acute and time-dependent effects of this type of exercise on VLDL-TG metabolism. Eight healthy sedentary men (age, 23.6 ± 6.1 years; body mass index, 23.1 ± 2.2 kg·m-2, peak oxygen consumption (V̇O2peak), 36.3 ± 5.5 mL·kg-1·min-1) participated in three stable isotopically labeled tracer infusion studies: (i) 14 h and (ii) 48 h after a single bout of high-intensity aerobic interval exercise (60% and 90% of V̇O2peak in 4 min intervals for a total of 32 min; gross energy expenditure ~500 kcal) and (iii) after an equivalent period of rest, in random order. Fasting plasma VLDL-TG concentration was 20% lower at 14 h (P = 0.046) but not at 48 h (P = 1.000) after exercise compared with the resting trial. VLDL-TG plasma clearance rate increased by 21% at 14 h (P < 0.001) but not at 48 h (P = 0.299) after exercise compared with rest, whereas hepatic VLDL-TG secretion rate was not different from rest at any time point after exercise. We conclude that high-intensity interval exercise reduces fasting plasma VLDL-TG concentrations in non-obese men the next day by augmenting VLDL-TG clearance, just like a single bout of continuous endurance exercise. This effect is short-lived and abolished by 48 h after exercise.

AB - A single bout of high-intensity interval aerobic exercise has been shown to produce the same or greater metabolic benefits as continuous endurance exercise with considerably less energy expenditure, but whether this applies to very low density lipoprotein (VLDL) metabolism is not known. We sought to examine the effect of a single bout of high-intensity interval aerobic exercise on basal VLDL-triglyceride (TG) kinetics 14 and 48 h after exercise cessation to determine the acute and time-dependent effects of this type of exercise on VLDL-TG metabolism. Eight healthy sedentary men (age, 23.6 ± 6.1 years; body mass index, 23.1 ± 2.2 kg·m-2, peak oxygen consumption (V̇O2peak), 36.3 ± 5.5 mL·kg-1·min-1) participated in three stable isotopically labeled tracer infusion studies: (i) 14 h and (ii) 48 h after a single bout of high-intensity aerobic interval exercise (60% and 90% of V̇O2peak in 4 min intervals for a total of 32 min; gross energy expenditure ~500 kcal) and (iii) after an equivalent period of rest, in random order. Fasting plasma VLDL-TG concentration was 20% lower at 14 h (P = 0.046) but not at 48 h (P = 1.000) after exercise compared with the resting trial. VLDL-TG plasma clearance rate increased by 21% at 14 h (P < 0.001) but not at 48 h (P = 0.299) after exercise compared with rest, whereas hepatic VLDL-TG secretion rate was not different from rest at any time point after exercise. We conclude that high-intensity interval exercise reduces fasting plasma VLDL-TG concentrations in non-obese men the next day by augmenting VLDL-TG clearance, just like a single bout of continuous endurance exercise. This effect is short-lived and abolished by 48 h after exercise.

KW - Aerobic

KW - Hypotriglyceridemia

KW - Kinetics

KW - Lean

KW - Physical activity

KW - Triacylglycerol

UR - http://www.scopus.com/inward/record.url?scp=84880261703&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880261703&partnerID=8YFLogxK

U2 - 10.1139/apnm-2012-0468

DO - 10.1139/apnm-2012-0468

M3 - Article

C2 - 23855269

AN - SCOPUS:84880261703

VL - 38

SP - 823

EP - 829

JO - Applied Physiology, Nutrition and Metabolism

JF - Applied Physiology, Nutrition and Metabolism

SN - 1715-5312

IS - 8

ER -