Effect of n-3 polyunsaturated fatty acid rich fish oil supplementation on serum biochemical profile in goat

The present study was designed to determine the effect of different levels of n-3 PUFA rich fish oil supplementation on serum biochemical profiles in goat. Goats (20) were divided into 4 equal groups (n,5) and supplemented with one of the 4 levels of EPA and DHA enriched fish oil to provide 0 mg (Control; CG); 78 mg/kg BW (T1); 156 mg/ kg BW (T2); and 312 mg/kg BW (T3) doses. The diets in all the groups were made isocaloric by adding palm oil. There was a treatment and day interaction for serum cholesterol concentration. Serum cholesterol in fish oil supplemented groups decreased with the increase in dose and indicated potential effect of n-3 PUFA rich fish oil on reducing the circulatory cholesterol concentration. There was a treatment and day interaction for serum triglycerides concentration at probability of 10%. The mean triglycerides concentration was lower in T2 and T3 on day 20 of supplementation than T1. Further, no effect of supplementation could be observed on serum NEFA concentration on different days of sampling. However, serum BHBA concentration had a treatment and day interaction. The mean concentration was lower in T3 than CG on day 38 of supplementation. The finding suggested that n-3 PUFA supplementation influenced serum biochemical profiles and dose-dependent effect was observed on reducing blood cholesterol concentration.