Effect of Obesity on Bone Healing After Foot and Ankle Long Bone Fractures

Jakob C. Thorud, Spencer Mortensen, Jennifer L. Thorud, Naohiro Shibuya, Yolanda Munoz Maldonado, Daniel Jupiter

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


As obesity has become more common, fractures in the obese population have become more frequent. Concern exists regarding alterations in bone health and healing in obese patients. A matched case-control study was performed at 1 institution to evaluate whether an association exists between nonunion and a high body mass index in metatarsal and ankle fractures. A total of 48 patients with nonunion were identified, and control patients matched 2 to 1 (n = 96) were selected. The control patients were matched for age, sex, and fracture type. No association was identified between nonunion and the continuous body mass index (p = .23) or morbid obesity, with a body mass index of ≥40 kg/m2 (p = .51). However, the results from both univariate and multivariate analysis suggested that patients with a current alcohol problem or a history of an alcohol problem might have a greater risk of nonunion. The odds ratio of a patient with a history of alcohol use experiencing nonunion was 2.7 (95% confidence interval 1.2 to 6.2). Further studies are warranted to confirm these findings.

Original languageEnglish (US)
Pages (from-to)258-262
Number of pages5
JournalJournal of Foot and Ankle Surgery
Issue number2
StatePublished - Mar 1 2017


  • alcohol
  • BMI
  • body mass index
  • fracture healing
  • metatarsal fracture

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Fingerprint Dive into the research topics of 'Effect of Obesity on Bone Healing After Foot and Ankle Long Bone Fractures'. Together they form a unique fingerprint.

Cite this