Effect of pinealectomy, binding, castration and melatonin on nerve growth factor levels in the submaxillary glands of mice

J. R. Perez-Polo, K. Hall, M. K. Vaughan, R. J. Reiter

    Research output: Contribution to journalArticle

    4 Scopus citations

    Abstract

    The effects of blinding alone or in combination with pinealectomy, castration and melatonin treatment on nerve growth factor (NGF) in submaxillary glands of mice were tested. Both pinealectomy and melatonin (placed subcutaneously in beeswax) treatment caused a marked reduction in NGF specific biological activity, esterase activity, and β-protein recovered from the submaxillary glands. Castrated mice also exhibited depressed levels of NGF in the salivary glands.

    Original languageEnglish (US)
    Pages (from-to)83-87
    Number of pages5
    JournalNeuroscience Letters
    Volume10
    Issue number1-2
    DOIs
    StatePublished - Nov 1978

    ASJC Scopus subject areas

    • Neuroscience(all)

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