Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe

Veronika V. Sapozhnikova, Roman V. Kuranov, Inga Cicenaite, Rinat O. Esenaliev, Donald S. Prough

    Research output: Contribution to journalArticlepeer-review

    34 Scopus citations

    Abstract

    We proposed to use optical coherence tomography (OCT) for continuous noninvasive blood glucose monitoring, and recently we significantly improved the sensitivity of this technique. The accuracy of OCT glucose monitoring is limited by several factors, including variation of tissue pressure exerted by the OCT probe. We studied the influence of high (>10kPa) and low (<1kPa) pressure levels on OCT blood glucose monitoring. We showed that controlling external pressure to <1kPa substantially improved the accuracy and reproducibility of OCT-based glucose monitoring.

    Original languageEnglish (US)
    Article number021112
    JournalJournal of Biomedical Optics
    Volume13
    Issue number2
    DOIs
    StatePublished - 2008

    Keywords

    • glucose
    • noninvasive monitoring
    • optical coherence tomography
    • pressure
    • tissue

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Biomaterials
    • Atomic and Molecular Physics, and Optics
    • Biomedical Engineering

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