Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe

Veronika V. Sapozhnikova, Roman V. Kuranov, Inga Cicenaite, Rinat O. Esenaliev, Donald S. Prough

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

We proposed to use optical coherence tomography (OCT) for continuous noninvasive blood glucose monitoring, and recently we significantly improved the sensitivity of this technique. The accuracy of OCT glucose monitoring is limited by several factors, including variation of tissue pressure exerted by the OCT probe. We studied the influence of high (>10kPa) and low (<1kPa) pressure levels on OCT blood glucose monitoring. We showed that controlling external pressure to <1kPa substantially improved the accuracy and reproducibility of OCT-based glucose monitoring.

Original languageEnglish (US)
Article number021112
JournalJournal of Biomedical Optics
Volume13
Issue number2
DOIs
StatePublished - Dec 1 2008

Keywords

  • glucose
  • noninvasive monitoring
  • optical coherence tomography
  • pressure
  • tissue

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

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