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Effective interventions to improve medication adherence in type 2 diabetes: A systematic review

  • Joni L. Strom Williams
  • , Rebekah J. Walker
  • , Brittany Smalls
  • , Jennifer A. Campbell
  • , Leonard E. Egede

Research output: Contribution to journalArticlepeer-review

Abstract

Aim
Medication adherence is associated with improved outcomes in diabetes. Interventions have been established to help improve medication adherence; however, the most effective interventions in patients with Type 2 diabetes remain unclear. The goal of this study was to distinguish whether interventions were effective and identify areas for future research.

Methods
Medline was searched for articles published between January 2000 and May 2013, and a reproducible strategy was used. Study eligibility criteria included interventions measuring medication adherence in adults with Type 2 diabetes.

Results
Twenty seven studies met the inclusion criteria and 13 showed a statistically significant change in medication adherence.

Conclusion
Heterogeneity of the study designs and measures of adherence made it difficult to identify effective interventions that improved medication adherence. Additionally, medication adherence may not be solely responsible for achieving glycemic control. Researchers must emphasize tailored interventions that optimize management and improve outcomes, and examine the need for clear indicators of medication adherence.
Original languageEnglish (US)
Pages (from-to)29-48
Number of pages20
JournalDiabetes Management
Volume4
Issue number1
DOIs
StatePublished - 2014
Externally publishedYes

Keywords

  • Diabetes type 2
  • Intervention
  • Medication adherence
  • Systematic Review

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