Effectiveness of Bivalirudin as a replacement for Heparin during cardiopulmonary bypass in patients undergoing coronary artery bypass grafting

Andreas Koster; Bruce Spiess; Derek P. Chew; Thomas Krabatsch; Luc Tambeur; Abe Deanda; Roland Hetzer; Hermann Kuppe; Nicholas G. Smedira; A. Michael Lincoff

doi:10.1016/j.amjcard.2003.10.021

Effectiveness of Bivalirudin as a replacement for Heparin during cardiopulmonary bypass in patients undergoing coronary artery bypass grafting

Andreas Koster, Bruce Spiess, Derek P. Chew, Thomas Krabatsch, Luc Tambeur, Abe Deanda, Roland Hetzer, Hermann Kuppe, Nicholas G. Smedira, A. Michael Lincoff

Research output: Contribution to journal › Article › peer-review

110 Scopus citations

Abstract

We investigated the use of bivalirudin as an anticoagulant therapy during cardiopulmonary bypass in 20 patients who underwent coronary artery bypass grafting. Primary end points consisted of clinical outcome data, whereas secondary end points focused on blood loss, transfusions, pharmacokinetics, and monitoring. Our data provide the first evidence of clinical feasibility of anticoagulation with bivalirudin during cardiopulmonary bypass.

Original language	English (US)
Pages (from-to)	356-359
Number of pages	4
Journal	American Journal of Cardiology
Volume	93
Issue number	3
DOIs	https://doi.org/10.1016/j.amjcard.2003.10.021
State	Published - Feb 1 2004
Externally published	Yes

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.amjcard.2003.10.021

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Koster, A., Spiess, B., Chew, D. P., Krabatsch, T., Tambeur, L., Deanda, A., Hetzer, R., Kuppe, H., Smedira, N. G., & Lincoff, A. M. (2004). Effectiveness of Bivalirudin as a replacement for Heparin during cardiopulmonary bypass in patients undergoing coronary artery bypass grafting. American Journal of Cardiology, 93(3), 356-359. https://doi.org/10.1016/j.amjcard.2003.10.021

Koster, A, Spiess, B, Chew, DP, Krabatsch, T, Tambeur, L, Deanda, A, Hetzer, R, Kuppe, H, Smedira, NG & Lincoff, AM 2004, 'Effectiveness of Bivalirudin as a replacement for Heparin during cardiopulmonary bypass in patients undergoing coronary artery bypass grafting', American Journal of Cardiology, vol. 93, no. 3, pp. 356-359. https://doi.org/10.1016/j.amjcard.2003.10.021

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AU - Tambeur, Luc

AU - Deanda, Abe

AU - Hetzer, Roland

AU - Kuppe, Hermann

AU - Smedira, Nicholas G.

AU - Lincoff, A. Michael

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Effectiveness of Bivalirudin as a replacement for Heparin during cardiopulmonary bypass in patients undergoing coronary artery bypass grafting

Abstract

ASJC Scopus subject areas

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