Effects of Antimurine Interleukin-6 on Bacterial Translocation During Gut-Derived Sepsis

Roberto Gennari, J. Wesley Alexander, Tonyia Pyles, Sharon Hartmann, Cora K. Ogle

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

Interleukin-6 appears to play a major role in both the intensity of translocation of E coli from the intestine following burn injury and the host's ability to kill translocated organisms. Improved outcome was associated with a reduction of IL-6 levels by anti—IL-6 antibody. (Arch Surg. 1994;129:1191-1197).

Original languageEnglish (US)
Pages (from-to)1191-1197
Number of pages7
JournalArchives of Surgery
Volume129
Issue number11
DOIs
StatePublished - Nov 1994
Externally publishedYes

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ASJC Scopus subject areas

  • Surgery

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