Effects of bombesin and somatostatin on secretion of neurotensin by medullary thyroid carcinoma

M. Marx, P. K. Seitz, C. M. Townsend, C. W. Cooper, G. H. Greeley, J. C. Thompson

Research output: Contribution to journalArticle

Abstract

Bombesin, which releases NT from the gut in dogs and man, also releases NT from rat MTC. The selective inhibition of NT release with STS suggests that BBS and CaCl2 may act by different mechanisms. This model provides unique opportunities for study of the synthesis, storage, and release of NT. BBS-stimulated NT release may be a useful clinical marker for patients with MTC.

Original languageEnglish (US)
Pages (from-to)207-208
Number of pages2
JournalSurgical Forum
VolumeVOL. 35
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Surgery

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    Marx, M., Seitz, P. K., Townsend, C. M., Cooper, C. W., Greeley, G. H., & Thompson, J. C. (1984). Effects of bombesin and somatostatin on secretion of neurotensin by medullary thyroid carcinoma. Surgical Forum, VOL. 35, 207-208.