Effects of Functional Disability and Depressive Symptoms on Mortality in Older Mexican–American Adults with Diabetes Mellitus

Miriam Mutambudzi, Nai Wei Chen, Kyriakos Markides, Soham Al Snih al snih

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objectives: To examine the effect of co-occurring depressive symptoms and functional disability on mortality in older Mexican–American adults with diabetes mellitus. Design: Longitudinal cohort study. Setting: Hispanic Established Populations for the Epidemiological Study of the Elderly (HEPESE) survey conducted in the southwestern United States (Texas, Colorado, Arizona, New Mexico, California). Participants: Community-dwelling Mexican Americans with self-reported diabetes mellitus participating in the HEPESE survey (N = 624). Measurements: Functional disability was assessed using a modified version of the Katz activity of daily living scale. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale. Mortality was determined by examining death certificates and reports from relatives. Cox proportional hazards regression analyses were used to examine the hazard of mortality as a function of co-occurring depressive symptoms and functional disability. Results: Over a 9.2-year follow-up, 391 participants died. Co-occurring high depressive symptoms and functional disability increased the risk of mortality (hazard ratio (HR) = 3.02, 95% confidence interval (CI) = 2.11–4.34). Risk was greater in men (HR = 8.11, 95% CI = 4.34–16.31) than women (HR = 2.21, 95% CI = 1.42–3.43). Conclusion: Co-occurring depressive symptoms and functional disability in older Mexican–American adults with diabetes mellitus increases mortality risk, especially in men. These findings have important implications for research, practice, and public health interventions.

Original languageEnglish (US)
Pages (from-to)e154-e159
JournalJournal of the American Geriatrics Society
Volume64
Issue number11
DOIs
StatePublished - Nov 1 2016

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Diabetes Mellitus
Depression
Mortality
Epidemiologic Studies
Confidence Intervals
Hispanic Americans
Southwestern United States
Public Health Practice
Independent Living
Death Certificates
Activities of Daily Living
Population
Longitudinal Studies
Cohort Studies
Regression Analysis
Research
Surveys and Questionnaires

Keywords

  • depressive symptoms
  • diabetes mellitus
  • functional disability
  • Mexican Americans
  • mortality

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

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title = "Effects of Functional Disability and Depressive Symptoms on Mortality in Older Mexican–American Adults with Diabetes Mellitus",
abstract = "Objectives: To examine the effect of co-occurring depressive symptoms and functional disability on mortality in older Mexican–American adults with diabetes mellitus. Design: Longitudinal cohort study. Setting: Hispanic Established Populations for the Epidemiological Study of the Elderly (HEPESE) survey conducted in the southwestern United States (Texas, Colorado, Arizona, New Mexico, California). Participants: Community-dwelling Mexican Americans with self-reported diabetes mellitus participating in the HEPESE survey (N = 624). Measurements: Functional disability was assessed using a modified version of the Katz activity of daily living scale. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale. Mortality was determined by examining death certificates and reports from relatives. Cox proportional hazards regression analyses were used to examine the hazard of mortality as a function of co-occurring depressive symptoms and functional disability. Results: Over a 9.2-year follow-up, 391 participants died. Co-occurring high depressive symptoms and functional disability increased the risk of mortality (hazard ratio (HR) = 3.02, 95{\%} confidence interval (CI) = 2.11–4.34). Risk was greater in men (HR = 8.11, 95{\%} CI = 4.34–16.31) than women (HR = 2.21, 95{\%} CI = 1.42–3.43). Conclusion: Co-occurring depressive symptoms and functional disability in older Mexican–American adults with diabetes mellitus increases mortality risk, especially in men. These findings have important implications for research, practice, and public health interventions.",
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author = "Miriam Mutambudzi and Chen, {Nai Wei} and Kyriakos Markides and {Al Snih al snih}, Soham",
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T1 - Effects of Functional Disability and Depressive Symptoms on Mortality in Older Mexican–American Adults with Diabetes Mellitus

AU - Mutambudzi, Miriam

AU - Chen, Nai Wei

AU - Markides, Kyriakos

AU - Al Snih al snih, Soham

PY - 2016/11/1

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N2 - Objectives: To examine the effect of co-occurring depressive symptoms and functional disability on mortality in older Mexican–American adults with diabetes mellitus. Design: Longitudinal cohort study. Setting: Hispanic Established Populations for the Epidemiological Study of the Elderly (HEPESE) survey conducted in the southwestern United States (Texas, Colorado, Arizona, New Mexico, California). Participants: Community-dwelling Mexican Americans with self-reported diabetes mellitus participating in the HEPESE survey (N = 624). Measurements: Functional disability was assessed using a modified version of the Katz activity of daily living scale. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale. Mortality was determined by examining death certificates and reports from relatives. Cox proportional hazards regression analyses were used to examine the hazard of mortality as a function of co-occurring depressive symptoms and functional disability. Results: Over a 9.2-year follow-up, 391 participants died. Co-occurring high depressive symptoms and functional disability increased the risk of mortality (hazard ratio (HR) = 3.02, 95% confidence interval (CI) = 2.11–4.34). Risk was greater in men (HR = 8.11, 95% CI = 4.34–16.31) than women (HR = 2.21, 95% CI = 1.42–3.43). Conclusion: Co-occurring depressive symptoms and functional disability in older Mexican–American adults with diabetes mellitus increases mortality risk, especially in men. These findings have important implications for research, practice, and public health interventions.

AB - Objectives: To examine the effect of co-occurring depressive symptoms and functional disability on mortality in older Mexican–American adults with diabetes mellitus. Design: Longitudinal cohort study. Setting: Hispanic Established Populations for the Epidemiological Study of the Elderly (HEPESE) survey conducted in the southwestern United States (Texas, Colorado, Arizona, New Mexico, California). Participants: Community-dwelling Mexican Americans with self-reported diabetes mellitus participating in the HEPESE survey (N = 624). Measurements: Functional disability was assessed using a modified version of the Katz activity of daily living scale. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale. Mortality was determined by examining death certificates and reports from relatives. Cox proportional hazards regression analyses were used to examine the hazard of mortality as a function of co-occurring depressive symptoms and functional disability. Results: Over a 9.2-year follow-up, 391 participants died. Co-occurring high depressive symptoms and functional disability increased the risk of mortality (hazard ratio (HR) = 3.02, 95% confidence interval (CI) = 2.11–4.34). Risk was greater in men (HR = 8.11, 95% CI = 4.34–16.31) than women (HR = 2.21, 95% CI = 1.42–3.43). Conclusion: Co-occurring depressive symptoms and functional disability in older Mexican–American adults with diabetes mellitus increases mortality risk, especially in men. These findings have important implications for research, practice, and public health interventions.

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