Effects of glutathione depletors on post-ischemic reperfusion in rat brain

G. Martinez, M. L. Carnazza, A. Campisi, V. Sorrenti, C. Di Giacomo, J. R. Perez-Polo, A. Vanella

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

The present paper reports the effects of GSH depletion (diethylmaleate induced) on partial cerebral ischemia and reperfusion for 7 and 20 days. Our results confirm that there is a paradoxical protective effect of the GSH- depletor and suggest an improved neuronal trophism induced by diethylmaleate treatment.

Original languageEnglish (US)
Pages (from-to)961-968
Number of pages8
JournalNeurochemical Research
Volume23
Issue number7
DOIs
StatePublished - 1998
Externally publishedYes

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Keywords

  • GSH-depletors
  • Ischemia
  • Reperfusion

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry

Cite this

Martinez, G., Carnazza, M. L., Campisi, A., Sorrenti, V., Di Giacomo, C., Perez-Polo, J. R., & Vanella, A. (1998). Effects of glutathione depletors on post-ischemic reperfusion in rat brain. Neurochemical Research, 23(7), 961-968. https://doi.org/10.1023/A:1021080321320