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Effects of glutathione depletors on post-ischemic reperfusion in rat brain

  • G. Martinez
  • , M. L. Carnazza
  • , A. Campisi
  • , V. Sorrenti
  • , C. Di Giacomo
  • , J. R. Perez-Polo
  • , A. Vanella

Research output: Contribution to journalArticlepeer-review

Abstract

The present paper reports the effects of GSH depletion (diethylmaleate induced) on partial cerebral ischemia and reperfusion for 7 and 20 days. Our results confirm that there is a paradoxical protective effect of the GSH- depletor and suggest an improved neuronal trophism induced by diethylmaleate treatment.

Original languageEnglish (US)
Pages (from-to)961-968
Number of pages8
JournalNeurochemical Research
Volume23
Issue number7
DOIs
StatePublished - 1998
Externally publishedYes

Keywords

  • GSH-depletors
  • Ischemia
  • Reperfusion

ASJC Scopus subject areas

  • Biochemistry
  • Cellular and Molecular Neuroscience

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