Effects of multiple injections of hCG on testis blood flow

Bard Geesaman, Javier Villanueva-Meyer, David Bluestein, Lance Miller, Ismael Mena, Jacob Rajfer

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Abstract

In attempting to determine whether or not multiple injections of human chorionic gonadotropin (hCG) augment testis blood flow, adult male rats were injected with three doses of 10 IU of hCG every other day and testis blood flow was determined on day 5, the day of the final injection. Testis blood flow (mL/100 g testis tissue/min ± SEM) as measured by the 133Xe washout method increased from 10.8 ± 1.3 to 20.4 ± 4.5 (p < 0.05) after the three doses of hCG. These observations suggest that multiple injections of hCG appear to have the same effect as a single dose of hCG in increasing testis blood flow. This supports the hypothesis that hCG should be administered to all patients undergoing orchiopexy in the hope that the increased perfusion of the gonad will make it less susceptible to ischemia during the surgical procedure.

Original languageEnglish (US)
Pages (from-to)81-83
Number of pages3
JournalUrology
Volume40
Issue number1
DOIs
StatePublished - Jan 1 1992
Externally publishedYes

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ASJC Scopus subject areas

  • Urology

Cite this

Geesaman, B., Villanueva-Meyer, J., Bluestein, D., Miller, L., Mena, I., & Rajfer, J. (1992). Effects of multiple injections of hCG on testis blood flow. Urology, 40(1), 81-83. https://doi.org/10.1016/0090-4295(92)90444-2