Effects of pressure rise on cw laser ablation of tissue

Gerald L. LeCarpentier, Massoud Motamedi, A. J. Welch

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The objectives of this research were to identify mechanisms responsible for the initiation of continuous wave (cw) laser ablation of tissue and investigate the role of pressure in the ablation process. Porcine aorta samples were irradiated in a chamber pressurized from 1×10 -4 to 12 atomospheres absolute pressure. Acrylic and Zn-Se windows in the experimental pressure chamber allowed video and infrared cameras to simultaneously record mechanical and thermal events associated with cw argon laser ablation of these samples. Video and thermal images of tissue slabs documented the explosive nature of cw laser ablation of soft biological media and revealed similar ablation threshold temperatures and ablation onset times under different environmental pressures; however, more violent initiation explosions with decreasing environmental pressures were observed. These results suggest that ablation initiates with thermal alterations in the mechanical strength of the tissue and proceeds with an explosion induced by the presence superheated liquid within the tissue.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsSteven L. Jacques, Abraham Katzir
PublisherPubl by Int Soc for Optical Engineering
Pages273-278
Number of pages6
Volume1427
StatePublished - 1991
Externally publishedYes
EventProceedings of Laser-Tissue Interaction II - Los Angeles, CA, USA
Duration: Jan 21 1991Jan 23 1991

Other

OtherProceedings of Laser-Tissue Interaction II
CityLos Angeles, CA, USA
Period1/21/911/23/91

Fingerprint

Continuous wave lasers
continuous wave lasers
Laser ablation
laser ablation
ablation
Ablation
Tissue
explosions
Explosions
argon lasers
aorta
pressure chambers
Argon lasers
slabs
chambers
cameras
Acrylics
Strength of materials
Cameras
thresholds

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

LeCarpentier, G. L., Motamedi, M., & Welch, A. J. (1991). Effects of pressure rise on cw laser ablation of tissue. In S. L. Jacques, & A. Katzir (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 1427, pp. 273-278). Publ by Int Soc for Optical Engineering.

Effects of pressure rise on cw laser ablation of tissue. / LeCarpentier, Gerald L.; Motamedi, Massoud; Welch, A. J.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / Steven L. Jacques; Abraham Katzir. Vol. 1427 Publ by Int Soc for Optical Engineering, 1991. p. 273-278.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

LeCarpentier, GL, Motamedi, M & Welch, AJ 1991, Effects of pressure rise on cw laser ablation of tissue. in SL Jacques & A Katzir (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 1427, Publ by Int Soc for Optical Engineering, pp. 273-278, Proceedings of Laser-Tissue Interaction II, Los Angeles, CA, USA, 1/21/91.
LeCarpentier GL, Motamedi M, Welch AJ. Effects of pressure rise on cw laser ablation of tissue. In Jacques SL, Katzir A, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 1427. Publ by Int Soc for Optical Engineering. 1991. p. 273-278
LeCarpentier, Gerald L. ; Motamedi, Massoud ; Welch, A. J. / Effects of pressure rise on cw laser ablation of tissue. Proceedings of SPIE - The International Society for Optical Engineering. editor / Steven L. Jacques ; Abraham Katzir. Vol. 1427 Publ by Int Soc for Optical Engineering, 1991. pp. 273-278
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