Effects of sex and gender on adaptation to space: Cardiovascular alterations

Steven H. Platts, C. Noel Bairey Merz, Yael Barr, Qi Fu, Martha Gulati, Richard Hughson, Benjamin D. Levine, Roxana Mehran, Nina Stachenfeld, Nanette K. Wenger

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Sex and gender differences in the cardiovascular adaptation to spaceflight were examined with the goal of optimizing the health and safety of male and female astronauts at the forefront of space exploration. Female astronauts are more susceptible to orthostatic intolerance after space flight; the visual impairment intracranial pressure syndrome predominates slightly in males. Since spaceflight simulates vascular aging, sex-specific effects on vascular endothelium and thrombotic risk warrant examination as predisposing factors to atherosclerosis, important as the current cohort of astronauts ages. Currently, 20% of astronauts are women, and the recently selected astronaut recruits are 50% women. Thus there should be expectation that future research will reflect the composition of the overall population to determine potential benefits or risks. This should apply both to clinical studies and to basic science research.

Original languageEnglish (US)
Pages (from-to)950-955
Number of pages6
JournalJournal of Women's Health
Volume23
Issue number11
DOIs
StatePublished - Nov 1 2014

Fingerprint

Astronauts
Space Flight
Orthostatic Intolerance
Vision Disorders
Vascular Endothelium
Intracranial Pressure
Sex Characteristics
Causality
Blood Vessels
Atherosclerosis
Safety
Health
Research
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Platts, S. H., Bairey Merz, C. N., Barr, Y., Fu, Q., Gulati, M., Hughson, R., ... Wenger, N. K. (2014). Effects of sex and gender on adaptation to space: Cardiovascular alterations. Journal of Women's Health, 23(11), 950-955. https://doi.org/10.1089/jwh.2014.4912

Effects of sex and gender on adaptation to space : Cardiovascular alterations. / Platts, Steven H.; Bairey Merz, C. Noel; Barr, Yael; Fu, Qi; Gulati, Martha; Hughson, Richard; Levine, Benjamin D.; Mehran, Roxana; Stachenfeld, Nina; Wenger, Nanette K.

In: Journal of Women's Health, Vol. 23, No. 11, 01.11.2014, p. 950-955.

Research output: Contribution to journalArticle

Platts, SH, Bairey Merz, CN, Barr, Y, Fu, Q, Gulati, M, Hughson, R, Levine, BD, Mehran, R, Stachenfeld, N & Wenger, NK 2014, 'Effects of sex and gender on adaptation to space: Cardiovascular alterations', Journal of Women's Health, vol. 23, no. 11, pp. 950-955. https://doi.org/10.1089/jwh.2014.4912
Platts SH, Bairey Merz CN, Barr Y, Fu Q, Gulati M, Hughson R et al. Effects of sex and gender on adaptation to space: Cardiovascular alterations. Journal of Women's Health. 2014 Nov 1;23(11):950-955. https://doi.org/10.1089/jwh.2014.4912
Platts, Steven H. ; Bairey Merz, C. Noel ; Barr, Yael ; Fu, Qi ; Gulati, Martha ; Hughson, Richard ; Levine, Benjamin D. ; Mehran, Roxana ; Stachenfeld, Nina ; Wenger, Nanette K. / Effects of sex and gender on adaptation to space : Cardiovascular alterations. In: Journal of Women's Health. 2014 ; Vol. 23, No. 11. pp. 950-955.
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