Effects of the Pit1 mutation on the insulin signaling pathway: Implications on the longevity of the long-lived Snell dwarf mouse

Keyphrases

• Insulin 100%
• Dwarf Mice 100%
• Long-lived 100%
• Snell Dwarf 100%
• Insulin Signaling Pathway 100%
• Insulin Receptor Substrate 1 (IRS1) 80%
• IGF Signaling 80%
• Decreased Activity 60%
• Phosphoinositide 3-kinase (PI3K) 40%
• Nematodes 40%
• IRS2 40%
• P110 40%
• Insulin-like Growth factor-1 20%
• Mouse Liver 20%
• Signal Transduction 20%
• Caenorhabditis Elegans 20%
• Growth Hormone Deficiency 20%
• Insulin Level 20%
• Hormonal Signaling 20%
• PI3K Pathway 20%

Biochemistry, Genetics and Molecular Biology

• Insulin Signaling 100%
• Snell Dwarf Mouse 100%
• Lifespan 66%
• Nematode 66%
• Signal Transduction 33%
• Candidate Gene 33%
• Dwarf Mouse 33%
• Caenorhabditis Elegans 33%
• Bovine Somatotropin 33%
• Insulin Level 33%
• Growth Hormone 33%
• Deficiency 33%

Agricultural and Biological Sciences

• Mouse 100%
• P110δ 33%
• Nematode 33%
• Growth Hormone Deficiency 16%
• Signal Transduction 16%
• Caenorhabditis Elegans 16%