Efficacy and safety of oral sodium phosphate versus polyethylene glycol solution for bowel preparation for colonoscopy

D. Nageshwar Reddy, G. V. Rao, Sreeram Parupudi

Research output: Contribution to journalArticle

18 Scopus citations


Objective: To assess the acceptability, safety and effectiveness of an oral sodium phosphate solution (Exelyte) for colon preparation prior to colonoscopy, compared with a polyethylene glycol solution (Peglec). Method: A colonoscopist-blinded, prospective, randomized, observational clinical study. Patients: One hundred patients undergoing colonoscopy for various indications were randomized (n=50 each) to receive either 90 mL of oral sodium phosphate mixed with 300 mL clear liquid and then consume about 4-5 glasses of water, or 2 liters of polyethylene glycol solution. Result: Sodium phosphate showed a safety profile similar to that of polyethylene glycol. However, patients tolerated it better. The colonoscopist reported similar cleansing of bowel in both groups. Conclusion: Oral sodium phosphate is well tolerated, is safe and provides bowel cleansing similar to that with a polyethylene glycol solution.

Original languageEnglish (US)
Pages (from-to)219-221
Number of pages3
JournalIndian Journal of Gastroenterology
Issue number6
StatePublished - Nov 2002
Externally publishedYes



  • Colon preparation

ASJC Scopus subject areas

  • Gastroenterology

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