Efficacy of a randomized trial examining commercial weight loss programs and exercise on metabolic syndrome in overweight and obese women

Claire Baetge, Conrad P. Earnest, Brittanie Lockard, Adriana M. Coletta, Elfego Galvan, Christopher Rasmussen, Kyle Levers, Sunday Y. Simbo, Y. Peter Jung, Majid Koozehchian, Jonathan Oliver, Ryan Dalton, Brittany Sanchez, Michael J. Byrd, Deepesh Khanna, Andrew Jagim, Julie Kresta, Mike Greenwood, Richard B. Kreider

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

While commercial dietary weight-loss programs typically advise exercise, few provide actual programing. The goal of this study was to compare the Curves Complete 90-day Challenge (CC, n = 29), which incorporates exercising and diet, to programs advocating exercise (Weight Watchers Points Plus (WW, n = 29), Jenny Craig At Home (JC, n = 27), and Nutrisystem Advance Select (NS, n = 28)) or control (n = 20) on metabolic syndrome (MetS) and weight loss. We randomized 133 sedentary, overweight women (age, 47 ± 11 years; body mass, 86 ± 14 kg; body mass index, 35 ± 6 kg/m2) into respective treatment groups for 12 weeks. Data were analyzed using chi square and general linear models adjusted for age and respective baseline measures. Data are means ± SD or mean change ± 95% confidence intervals (CIs). We observed a significant trend for a reduction in energy intake for all treatment groups and significant weight loss for all groups except control: CC (−4.32 kg; 95% CI, −5.75, −2.88), WW (−4.31 kg; 95% CI, −5.82, −2.96), JC (−5.34 kg; 95% CI, −6.86, −3.90), NS (−5.03 kg; 95% CI, −6.49, −3.56), and control (0.16 kg, 95% CI, −1.56, 1.89). Reduced MetS prevalence was observed at follow-up for CC (35% vs. 14%, adjusted standardized residuals (adjres.) = 3.1), but notWW(31% vs. 28% adjres. = 0.5), JC (37% vs. 42%, adjres. = −0.7), NS (39% vs. 50% adjres. = −1.5), or control (45% vs. 55% adjres. = −1.7). While all groups improved relative fitness (mL·kg−1·min−1) because of weight loss, only the CC group improved absolute fitness (L/min). In conclusion, commercial programs offering concurrent diet and exercise programming appear to offer greater improvements in MetS prevalence and cardiovascular function after 12 weeks of intervention.

Original languageEnglish (US)
Pages (from-to)216-227
Number of pages12
JournalApplied Physiology, Nutrition and Metabolism
Volume42
Issue number2
DOIs
StatePublished - 2017

Fingerprint

Weight Reduction Programs
Confidence Intervals
Exercise
Weight Loss
Metabolic Syndrome X
Diet
Energy Intake
Linear Models
Body Mass Index
Weights and Measures
Control Groups
Therapeutics

Keywords

  • Diet
  • Exercise
  • Metabolic syndrome

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Physiology
  • Nutrition and Dietetics
  • Physiology (medical)

Cite this

Efficacy of a randomized trial examining commercial weight loss programs and exercise on metabolic syndrome in overweight and obese women. / Baetge, Claire; Earnest, Conrad P.; Lockard, Brittanie; Coletta, Adriana M.; Galvan, Elfego; Rasmussen, Christopher; Levers, Kyle; Simbo, Sunday Y.; Jung, Y. Peter; Koozehchian, Majid; Oliver, Jonathan; Dalton, Ryan; Sanchez, Brittany; Byrd, Michael J.; Khanna, Deepesh; Jagim, Andrew; Kresta, Julie; Greenwood, Mike; Kreider, Richard B.

In: Applied Physiology, Nutrition and Metabolism, Vol. 42, No. 2, 2017, p. 216-227.

Research output: Contribution to journalArticle

Baetge, C, Earnest, CP, Lockard, B, Coletta, AM, Galvan, E, Rasmussen, C, Levers, K, Simbo, SY, Jung, YP, Koozehchian, M, Oliver, J, Dalton, R, Sanchez, B, Byrd, MJ, Khanna, D, Jagim, A, Kresta, J, Greenwood, M & Kreider, RB 2017, 'Efficacy of a randomized trial examining commercial weight loss programs and exercise on metabolic syndrome in overweight and obese women', Applied Physiology, Nutrition and Metabolism, vol. 42, no. 2, pp. 216-227. https://doi.org/10.1139/apnm-2016-0456
Baetge, Claire ; Earnest, Conrad P. ; Lockard, Brittanie ; Coletta, Adriana M. ; Galvan, Elfego ; Rasmussen, Christopher ; Levers, Kyle ; Simbo, Sunday Y. ; Jung, Y. Peter ; Koozehchian, Majid ; Oliver, Jonathan ; Dalton, Ryan ; Sanchez, Brittany ; Byrd, Michael J. ; Khanna, Deepesh ; Jagim, Andrew ; Kresta, Julie ; Greenwood, Mike ; Kreider, Richard B. / Efficacy of a randomized trial examining commercial weight loss programs and exercise on metabolic syndrome in overweight and obese women. In: Applied Physiology, Nutrition and Metabolism. 2017 ; Vol. 42, No. 2. pp. 216-227.
@article{97667a10f3544706a4b097f7966542f2,
title = "Efficacy of a randomized trial examining commercial weight loss programs and exercise on metabolic syndrome in overweight and obese women",
abstract = "While commercial dietary weight-loss programs typically advise exercise, few provide actual programing. The goal of this study was to compare the Curves Complete 90-day Challenge (CC, n = 29), which incorporates exercising and diet, to programs advocating exercise (Weight Watchers Points Plus (WW, n = 29), Jenny Craig At Home (JC, n = 27), and Nutrisystem Advance Select (NS, n = 28)) or control (n = 20) on metabolic syndrome (MetS) and weight loss. We randomized 133 sedentary, overweight women (age, 47 ± 11 years; body mass, 86 ± 14 kg; body mass index, 35 ± 6 kg/m2) into respective treatment groups for 12 weeks. Data were analyzed using chi square and general linear models adjusted for age and respective baseline measures. Data are means ± SD or mean change ± 95{\%} confidence intervals (CIs). We observed a significant trend for a reduction in energy intake for all treatment groups and significant weight loss for all groups except control: CC (−4.32 kg; 95{\%} CI, −5.75, −2.88), WW (−4.31 kg; 95{\%} CI, −5.82, −2.96), JC (−5.34 kg; 95{\%} CI, −6.86, −3.90), NS (−5.03 kg; 95{\%} CI, −6.49, −3.56), and control (0.16 kg, 95{\%} CI, −1.56, 1.89). Reduced MetS prevalence was observed at follow-up for CC (35{\%} vs. 14{\%}, adjusted standardized residuals (adjres.) = 3.1), but notWW(31{\%} vs. 28{\%} adjres. = 0.5), JC (37{\%} vs. 42{\%}, adjres. = −0.7), NS (39{\%} vs. 50{\%} adjres. = −1.5), or control (45{\%} vs. 55{\%} adjres. = −1.7). While all groups improved relative fitness (mL·kg−1·min−1) because of weight loss, only the CC group improved absolute fitness (L/min). In conclusion, commercial programs offering concurrent diet and exercise programming appear to offer greater improvements in MetS prevalence and cardiovascular function after 12 weeks of intervention.",
keywords = "Diet, Exercise, Metabolic syndrome",
author = "Claire Baetge and Earnest, {Conrad P.} and Brittanie Lockard and Coletta, {Adriana M.} and Elfego Galvan and Christopher Rasmussen and Kyle Levers and Simbo, {Sunday Y.} and Jung, {Y. Peter} and Majid Koozehchian and Jonathan Oliver and Ryan Dalton and Brittany Sanchez and Byrd, {Michael J.} and Deepesh Khanna and Andrew Jagim and Julie Kresta and Mike Greenwood and Kreider, {Richard B.}",
year = "2017",
doi = "10.1139/apnm-2016-0456",
language = "English (US)",
volume = "42",
pages = "216--227",
journal = "Applied Physiology, Nutrition and Metabolism",
issn = "1715-5312",
publisher = "National Research Council of Canada",
number = "2",

}

TY - JOUR

T1 - Efficacy of a randomized trial examining commercial weight loss programs and exercise on metabolic syndrome in overweight and obese women

AU - Baetge, Claire

AU - Earnest, Conrad P.

AU - Lockard, Brittanie

AU - Coletta, Adriana M.

AU - Galvan, Elfego

AU - Rasmussen, Christopher

AU - Levers, Kyle

AU - Simbo, Sunday Y.

AU - Jung, Y. Peter

AU - Koozehchian, Majid

AU - Oliver, Jonathan

AU - Dalton, Ryan

AU - Sanchez, Brittany

AU - Byrd, Michael J.

AU - Khanna, Deepesh

AU - Jagim, Andrew

AU - Kresta, Julie

AU - Greenwood, Mike

AU - Kreider, Richard B.

PY - 2017

Y1 - 2017

N2 - While commercial dietary weight-loss programs typically advise exercise, few provide actual programing. The goal of this study was to compare the Curves Complete 90-day Challenge (CC, n = 29), which incorporates exercising and diet, to programs advocating exercise (Weight Watchers Points Plus (WW, n = 29), Jenny Craig At Home (JC, n = 27), and Nutrisystem Advance Select (NS, n = 28)) or control (n = 20) on metabolic syndrome (MetS) and weight loss. We randomized 133 sedentary, overweight women (age, 47 ± 11 years; body mass, 86 ± 14 kg; body mass index, 35 ± 6 kg/m2) into respective treatment groups for 12 weeks. Data were analyzed using chi square and general linear models adjusted for age and respective baseline measures. Data are means ± SD or mean change ± 95% confidence intervals (CIs). We observed a significant trend for a reduction in energy intake for all treatment groups and significant weight loss for all groups except control: CC (−4.32 kg; 95% CI, −5.75, −2.88), WW (−4.31 kg; 95% CI, −5.82, −2.96), JC (−5.34 kg; 95% CI, −6.86, −3.90), NS (−5.03 kg; 95% CI, −6.49, −3.56), and control (0.16 kg, 95% CI, −1.56, 1.89). Reduced MetS prevalence was observed at follow-up for CC (35% vs. 14%, adjusted standardized residuals (adjres.) = 3.1), but notWW(31% vs. 28% adjres. = 0.5), JC (37% vs. 42%, adjres. = −0.7), NS (39% vs. 50% adjres. = −1.5), or control (45% vs. 55% adjres. = −1.7). While all groups improved relative fitness (mL·kg−1·min−1) because of weight loss, only the CC group improved absolute fitness (L/min). In conclusion, commercial programs offering concurrent diet and exercise programming appear to offer greater improvements in MetS prevalence and cardiovascular function after 12 weeks of intervention.

AB - While commercial dietary weight-loss programs typically advise exercise, few provide actual programing. The goal of this study was to compare the Curves Complete 90-day Challenge (CC, n = 29), which incorporates exercising and diet, to programs advocating exercise (Weight Watchers Points Plus (WW, n = 29), Jenny Craig At Home (JC, n = 27), and Nutrisystem Advance Select (NS, n = 28)) or control (n = 20) on metabolic syndrome (MetS) and weight loss. We randomized 133 sedentary, overweight women (age, 47 ± 11 years; body mass, 86 ± 14 kg; body mass index, 35 ± 6 kg/m2) into respective treatment groups for 12 weeks. Data were analyzed using chi square and general linear models adjusted for age and respective baseline measures. Data are means ± SD or mean change ± 95% confidence intervals (CIs). We observed a significant trend for a reduction in energy intake for all treatment groups and significant weight loss for all groups except control: CC (−4.32 kg; 95% CI, −5.75, −2.88), WW (−4.31 kg; 95% CI, −5.82, −2.96), JC (−5.34 kg; 95% CI, −6.86, −3.90), NS (−5.03 kg; 95% CI, −6.49, −3.56), and control (0.16 kg, 95% CI, −1.56, 1.89). Reduced MetS prevalence was observed at follow-up for CC (35% vs. 14%, adjusted standardized residuals (adjres.) = 3.1), but notWW(31% vs. 28% adjres. = 0.5), JC (37% vs. 42%, adjres. = −0.7), NS (39% vs. 50% adjres. = −1.5), or control (45% vs. 55% adjres. = −1.7). While all groups improved relative fitness (mL·kg−1·min−1) because of weight loss, only the CC group improved absolute fitness (L/min). In conclusion, commercial programs offering concurrent diet and exercise programming appear to offer greater improvements in MetS prevalence and cardiovascular function after 12 weeks of intervention.

KW - Diet

KW - Exercise

KW - Metabolic syndrome

UR - http://www.scopus.com/inward/record.url?scp=85011340533&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85011340533&partnerID=8YFLogxK

U2 - 10.1139/apnm-2016-0456

DO - 10.1139/apnm-2016-0456

M3 - Article

C2 - 28044449

AN - SCOPUS:85011340533

VL - 42

SP - 216

EP - 227

JO - Applied Physiology, Nutrition and Metabolism

JF - Applied Physiology, Nutrition and Metabolism

SN - 1715-5312

IS - 2

ER -