Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru

Alan J. Magill; Jorge Zegarra; Coralith Garcia; Wilmer Marquiño; Trenton K. Ruebush

doi:10.1590/S0037-86822004000300015

Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru

Alan J. Magill, Jorge Zegarra, Coralith Garcia, Wilmer Marquiño, Trenton K. Ruebush

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

In vivo antimalarial drug efficacy studies of uncomplicated Plasmodiumfalciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of resistance to mefloquine.

Original language	English (US)
Pages (from-to)	279-281
Number of pages	3
Journal	Revista da Sociedade Brasileira de Medicina Tropical
Volume	37
Issue number	3
DOIs	https://doi.org/10.1590/S0037-86822004000300015
State	Published - 2004
Externally published	Yes

Keywords

Antimalarial drug resistance
Mefloquine
Peru
Plasmodium falciparum
Sulfadoxine- pyrimethamine

ASJC Scopus subject areas

Parasitology
Microbiology (medical)
Infectious Diseases

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abstract = "In vivo antimalarial drug efficacy studies of uncomplicated Plasmodiumfalciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of resistance to mefloquine.",

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AU - Magill, Alan J.

AU - Zegarra, Jorge

AU - Garcia, Coralith

AU - Marquiño, Wilmer

AU - Ruebush, Trenton K.

PY - 2004

Y1 - 2004

N2 - In vivo antimalarial drug efficacy studies of uncomplicated Plasmodiumfalciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of resistance to mefloquine.

AB - In vivo antimalarial drug efficacy studies of uncomplicated Plasmodiumfalciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of resistance to mefloquine.

KW - Antimalarial drug resistance

KW - Mefloquine

KW - Peru

KW - Plasmodium falciparum

KW - Sulfadoxine- pyrimethamine

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ER -

Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru

Abstract

Keywords

ASJC Scopus subject areas

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