Ehrlichia chaffeensis is an obligately intracellular gram negative bacterium with a small genome that thrives in mammalian mononuclear phagocytes by exploiting eukaryotic processes. Herein, we discuss the latest findings on moonlighting tandem repeat protein effectors and their secretion mechanisms, and novel molecular interkingdom interactions that provide insight into the intracellular pathobiology of ehrlichiae.
- Human monocytotropic ehrlichiosis
- Moonlighting protein
- Post translational modification
- Tandem repeat protein
- Type 1 secretion system
ASJC Scopus subject areas
- Infectious Diseases