Ehrlichia SLiM Ligand Mimetic Activates Notch Signaling in Human Monocytes

Keyphrases

• Ehrlichia 100%
• Human Monocytes 100%
• Notch Signaling 100%
• Short Linear Motifs (SLiMs) 100%
• Notch Ligands 50%
• Notch Receptors 50%
• Notch Activation 50%
• Tandem Domains 37%
• Signaling Pathway 25%
• Tandem Repeats 25%
• Receptor-ligand Interaction 25%
• Mononuclear Phagocytes 25%
• Evolutionarily Conserved 25%
• Evade 25%
• Cell Function 12%
• Nuclear Translocation 12%
• Innate Immunity 12%
• Gene Expression 12%
• Biological Function 12%
• Cell Signaling Pathways 12%
• Ehrlichia Chaffeensis 12%
• Amino Acids 12%
• Receptor Activation 12%
• Direct Interaction 12%
• Downstream Genes 12%
• Endogenous Ligand 12%
• Immune Defense 12%
• Peptide Mapping 12%
• Host Signals 12%
• Innate Immune Cells 12%
• Mimicry 12%
• Molecular Mimicry 12%
• Cell Signaling 12%
• Cellular Activation 12%
• Effector Proteins 12%
• Colocalization 12%
• Tandem Repeat Protein 12%
• Negative Regulator 12%
• Associated Sequence 12%
• Sequence Homology 12%
• Ubiquitin Ligase Activity 12%
• Cell Fate 12%
• Innate Immune Defense 12%
• Innate Host Defense 12%
• Cell Reprogramming 12%
• Signaling Genes 12%
• Notch1 12%
• WD Repeat Domain 12%
• Reprogramming Strategies 12%
• F-box 12%
• FBW7 12%
• Specific Molecular Interactions 12%
• Disease-causing Pathogens 12%
• Molecular Motifs 12%
• Non-canonical Notch 12%

Biochemistry, Genetics and Molecular Biology

• Monocyte 100%
• Ehrlichia 100%
• Notch 100%
• Notch Signaling Pathway 100%
• Short Linear Motif 100%
• Tandem Repeat 46%
• Signal Transduction 46%
• Infectious Agent 30%
• Notch Proteins 30%
• Mononuclear Phagocyte 15%
• Gene Expression 7%
• Biological Functions 7%
• Amino Acids 7%
• Cell Function 7%
• Innate Immunity 7%
• Host Resistance 7%
• Reprogramming 7%
• Immunity 7%
• Molecular Interaction 7%
• Immunocompetent Cell 7%
• Cell Fate 7%
• Ehrlichia Chaffeensis 7%
• Sequence Homology 7%
• Ubiquitin Ligase 7%
• WD40 Repeat 7%
• Immune Evasion 7%
• Notch-1 7%
• Molecular Mimicry 7%
• Nuclear Reprogramming 7%

Immunology and Microbiology

• Monocyte 100%
• Ehrlichia 100%
• Notch 100%
• Notch Signaling 100%
• Signal Transduction 33%
• Tandem Repeat 33%
• Infectious Agent 22%
• Mononuclear Phagocyte 11%
• Cell Function 5%
• Innate Immune System 5%
• Host Cell 5%
• Biological Functions 5%
• Gene Expression 5%
• Host Resistance 5%
• Immunocompetent Cell 5%
• Ehrlichia Chaffeensis 5%
• Immune Evasion 5%
• Immunity 5%
• Molecular Interaction 5%
• Molecular Mimicry 5%
• Cell Fate 5%
• Sequence Homology 5%
• WD Repeat 5%
• Nuclear Reprogramming 5%