Ehrlichia species in Rhipicephalus sanguineus ticks in Cameroon

Lucy M. Ndip, Roland N. Ndip, Veronica E. Ndive, Jane A. Awuh, David Walker, Jere McBride

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Ehrlichia and Anaplasma species are tick-transmitted obligately intracellular bacteria that commonly cause disease in dogs worldwide. In addition to causing disease in canines, Ehrlichia chaffeensis, Ehrlichia ewingii, and Anaplasma phagocytophilum are responsible for emerging and life-threatening human zoonoses in the United States. We previously reported a high prevalence of E. canis infection in Cameroonian dogs based on serologic and molecular evidence. This study was undertaken to determine the Ehrlichia species (E. canis, E. chaffeensis, E. ewingii) present in Rhipicephalus sanguineus ticks (n = 92) collected from those dogs (n = 51). Ehrlichial DNA was detected by real-time polymerase chain reaction (PCR) in 28 (30%) unengorged R. sanguineus ticks attached to dogs. E. canis, the causative agent of canine monocytic ehrlichiosis, was detected in 19 (21%) ticks from 15 dogs, E. ewingii was detected in six (6%) ticks from 6 dogs, and E. chaffeensis, the etiologic agent of human monocytotropic ehrlichiosis, was detected in 4 (4%) ticks. Notably, 2 ticks were coinfected with E. chaffeensis and E. canis, one tick with E. canis and E. ewingii, and one tick with E. chaffeensis and E. ewingii. These findings further support our previous conclusion that multiple Ehrlichia species are present in Cameroon and identify R. sanguineus ticks primarily infected with E. canis, but suggest that they may be infected with and transmit other ehrlichial agents in Cameroon, potentially to humans.

Original languageEnglish (US)
Pages (from-to)221-227
Number of pages7
JournalVector-Borne and Zoonotic Diseases
Volume7
Issue number2
DOIs
StatePublished - Jun 2007

Fingerprint

Rhipicephalus sanguineus
Ehrlichia
Cameroon
Ehrlichia chaffeensis
Ticks
Dogs
Anaplasma phagocytophilum
Ehrlichiosis
Dog Diseases
Anaplasma
Zoonoses

Keywords

  • Canine
  • Ehrlichia
  • Rhipicephalus

ASJC Scopus subject areas

  • Infectious Diseases
  • Parasitology

Cite this

Ehrlichia species in Rhipicephalus sanguineus ticks in Cameroon. / Ndip, Lucy M.; Ndip, Roland N.; Ndive, Veronica E.; Awuh, Jane A.; Walker, David; McBride, Jere.

In: Vector-Borne and Zoonotic Diseases, Vol. 7, No. 2, 06.2007, p. 221-227.

Research output: Contribution to journalArticle

Ndip, Lucy M. ; Ndip, Roland N. ; Ndive, Veronica E. ; Awuh, Jane A. ; Walker, David ; McBride, Jere. / Ehrlichia species in Rhipicephalus sanguineus ticks in Cameroon. In: Vector-Borne and Zoonotic Diseases. 2007 ; Vol. 7, No. 2. pp. 221-227.
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