Electroacupuncture analgesia in rat ankle sprain pain model

Neural mechanisms

Hee Young Kim, Sung Tae Koo, Jae Hyo Kim, Kyungeh An, Kyungsoon Chung, Jin Chung

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Objectives: Acupuncture, an alternative medical therapy with a long history, is appealing because it can activate endogenous analgesic mechanisms by minimally invasive means. The mechanisms of acupuncture, however, are not well understood yet. The following sentence was removed from our original manuscript. One of the major problems impeding understanding of the acupuncture mechanism is lack of experimental models that mimic various forms of persistent pain that respond to acupuncture in humans. Methods: In this review, we summarize and discuss previous and recent findings regarding electroacupuncture-induced analgesia in an ankle sprain pain model and the potential underlying mechanisms of acupuncture. Results: A novel model of ankle sprain pain is introduced recently and the mechanism of electroacupuncture-induced analgesia in this model has been explored. The following sentence was removed from our original manuscript. This model provides a reproducible and quantifiable index of persistent pain at the ankle joint in rats. Acupuncture at a remote site produces longlasting and powerful analgesia. The consistent analgesic effect of acupuncture in this model has allowed us to pursue the underlying neural mechanisms. Conclusions: These studies provide insight into the mechanisms of acupuncture analgesia in one particular form of persistent pain, and hopefully will allow us to expand our knowledge to other painful conditions. [Neurol Res 2010; 32: 10-17]

Original languageEnglish (US)
JournalNeurological Research
Volume32
Issue numberSUPPL.1
DOIs
StatePublished - Feb 2010

Fingerprint

Ankle Injuries
Electroacupuncture
Acupuncture
Analgesia
Pain
Manuscripts
Analgesics
Acupuncture Analgesia
Ankle Joint
Complementary Therapies
Theoretical Models
History

Keywords

  • Analgesia
  • Ankle sprain pain
  • Electroacupuncture
  • Neural mechanisms

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Electroacupuncture analgesia in rat ankle sprain pain model : Neural mechanisms. / Kim, Hee Young; Koo, Sung Tae; Kim, Jae Hyo; An, Kyungeh; Chung, Kyungsoon; Chung, Jin.

In: Neurological Research, Vol. 32, No. SUPPL.1, 02.2010.

Research output: Contribution to journalArticle

Kim, Hee Young ; Koo, Sung Tae ; Kim, Jae Hyo ; An, Kyungeh ; Chung, Kyungsoon ; Chung, Jin. / Electroacupuncture analgesia in rat ankle sprain pain model : Neural mechanisms. In: Neurological Research. 2010 ; Vol. 32, No. SUPPL.1.
@article{3c706d7478e74b019ec19dc8b474b593,
title = "Electroacupuncture analgesia in rat ankle sprain pain model: Neural mechanisms",
abstract = "Objectives: Acupuncture, an alternative medical therapy with a long history, is appealing because it can activate endogenous analgesic mechanisms by minimally invasive means. The mechanisms of acupuncture, however, are not well understood yet. The following sentence was removed from our original manuscript. One of the major problems impeding understanding of the acupuncture mechanism is lack of experimental models that mimic various forms of persistent pain that respond to acupuncture in humans. Methods: In this review, we summarize and discuss previous and recent findings regarding electroacupuncture-induced analgesia in an ankle sprain pain model and the potential underlying mechanisms of acupuncture. Results: A novel model of ankle sprain pain is introduced recently and the mechanism of electroacupuncture-induced analgesia in this model has been explored. The following sentence was removed from our original manuscript. This model provides a reproducible and quantifiable index of persistent pain at the ankle joint in rats. Acupuncture at a remote site produces longlasting and powerful analgesia. The consistent analgesic effect of acupuncture in this model has allowed us to pursue the underlying neural mechanisms. Conclusions: These studies provide insight into the mechanisms of acupuncture analgesia in one particular form of persistent pain, and hopefully will allow us to expand our knowledge to other painful conditions. [Neurol Res 2010; 32: 10-17]",
keywords = "Analgesia, Ankle sprain pain, Electroacupuncture, Neural mechanisms",
author = "Kim, {Hee Young} and Koo, {Sung Tae} and Kim, {Jae Hyo} and Kyungeh An and Kyungsoon Chung and Jin Chung",
year = "2010",
month = "2",
doi = "10.1179/016164109X",
language = "English (US)",
volume = "32",
journal = "Neurological Research",
issn = "0161-6412",
publisher = "Maney Publishing",
number = "SUPPL.1",

}

TY - JOUR

T1 - Electroacupuncture analgesia in rat ankle sprain pain model

T2 - Neural mechanisms

AU - Kim, Hee Young

AU - Koo, Sung Tae

AU - Kim, Jae Hyo

AU - An, Kyungeh

AU - Chung, Kyungsoon

AU - Chung, Jin

PY - 2010/2

Y1 - 2010/2

N2 - Objectives: Acupuncture, an alternative medical therapy with a long history, is appealing because it can activate endogenous analgesic mechanisms by minimally invasive means. The mechanisms of acupuncture, however, are not well understood yet. The following sentence was removed from our original manuscript. One of the major problems impeding understanding of the acupuncture mechanism is lack of experimental models that mimic various forms of persistent pain that respond to acupuncture in humans. Methods: In this review, we summarize and discuss previous and recent findings regarding electroacupuncture-induced analgesia in an ankle sprain pain model and the potential underlying mechanisms of acupuncture. Results: A novel model of ankle sprain pain is introduced recently and the mechanism of electroacupuncture-induced analgesia in this model has been explored. The following sentence was removed from our original manuscript. This model provides a reproducible and quantifiable index of persistent pain at the ankle joint in rats. Acupuncture at a remote site produces longlasting and powerful analgesia. The consistent analgesic effect of acupuncture in this model has allowed us to pursue the underlying neural mechanisms. Conclusions: These studies provide insight into the mechanisms of acupuncture analgesia in one particular form of persistent pain, and hopefully will allow us to expand our knowledge to other painful conditions. [Neurol Res 2010; 32: 10-17]

AB - Objectives: Acupuncture, an alternative medical therapy with a long history, is appealing because it can activate endogenous analgesic mechanisms by minimally invasive means. The mechanisms of acupuncture, however, are not well understood yet. The following sentence was removed from our original manuscript. One of the major problems impeding understanding of the acupuncture mechanism is lack of experimental models that mimic various forms of persistent pain that respond to acupuncture in humans. Methods: In this review, we summarize and discuss previous and recent findings regarding electroacupuncture-induced analgesia in an ankle sprain pain model and the potential underlying mechanisms of acupuncture. Results: A novel model of ankle sprain pain is introduced recently and the mechanism of electroacupuncture-induced analgesia in this model has been explored. The following sentence was removed from our original manuscript. This model provides a reproducible and quantifiable index of persistent pain at the ankle joint in rats. Acupuncture at a remote site produces longlasting and powerful analgesia. The consistent analgesic effect of acupuncture in this model has allowed us to pursue the underlying neural mechanisms. Conclusions: These studies provide insight into the mechanisms of acupuncture analgesia in one particular form of persistent pain, and hopefully will allow us to expand our knowledge to other painful conditions. [Neurol Res 2010; 32: 10-17]

KW - Analgesia

KW - Ankle sprain pain

KW - Electroacupuncture

KW - Neural mechanisms

UR - http://www.scopus.com/inward/record.url?scp=77949453096&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77949453096&partnerID=8YFLogxK

U2 - 10.1179/016164109X

DO - 10.1179/016164109X

M3 - Article

VL - 32

JO - Neurological Research

JF - Neurological Research

SN - 0161-6412

IS - SUPPL.1

ER -