Electrophysiological and histological studies of laser and suture anastomosis in rat sciatic nerve

T. A. Benke, J. W. Clark, P. J. Wisoff, S. A. Shehab, S. Schneider, B. Chidambaram, H. Hawkins, J. Laurent

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In order to compare the effects of the two repair techniques, a controlled study was devised in which the right sciatic nerve of Sprague-Dawley rats was surgically cut and reanastomosed by means of either four epineurial sutures or two epineurial sutures and CO 2 laser welds. After a mean of 11 months, both sciatic nerves were excised. The conduction velocities recorded for suture-and laser-assist-repaired nerves were not found to be significantly different. However, laser-repaired nerves exhibited lower conduction failure rates and lower stimulation thresholds than nerves with conventional suture repair. No apparent difference in the diameter of myelinated fibers distal to the anastomosis in either of the two repair categories was observed. Sutured nerves exhibited greater branching of myelinated axons proximal to the anastomosis and at the same time permitted fewer axons through the anastomosis as compared to laser-repaired nerves. It is suggested that this could explained the greater incidence of neuroma formation in sutured nerves as well as the diminished conduction.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherPubl by Alliance for Engineering in Medicine & Biology
Pages1174-1175
Number of pages2
Volume11 pt 4
StatePublished - 1989
Externally publishedYes
EventImages of the Twenty-First Century - Proceedings of the 11th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2 - Seattle, WA, USA
Duration: Nov 9 1989Nov 12 1989

Other

OtherImages of the Twenty-First Century - Proceedings of the 11th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2
CitySeattle, WA, USA
Period11/9/8911/12/89

Fingerprint

Rats
Repair
Lasers
Carbon Monoxide
Welds
Fibers
Axons

ASJC Scopus subject areas

  • Bioengineering
  • Engineering(all)

Cite this

Benke, T. A., Clark, J. W., Wisoff, P. J., Shehab, S. A., Schneider, S., Chidambaram, B., ... Laurent, J. (1989). Electrophysiological and histological studies of laser and suture anastomosis in rat sciatic nerve. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 11 pt 4, pp. 1174-1175). Publ by Alliance for Engineering in Medicine & Biology.

Electrophysiological and histological studies of laser and suture anastomosis in rat sciatic nerve. / Benke, T. A.; Clark, J. W.; Wisoff, P. J.; Shehab, S. A.; Schneider, S.; Chidambaram, B.; Hawkins, H.; Laurent, J.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 11 pt 4 Publ by Alliance for Engineering in Medicine & Biology, 1989. p. 1174-1175.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Benke, TA, Clark, JW, Wisoff, PJ, Shehab, SA, Schneider, S, Chidambaram, B, Hawkins, H & Laurent, J 1989, Electrophysiological and histological studies of laser and suture anastomosis in rat sciatic nerve. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 11 pt 4, Publ by Alliance for Engineering in Medicine & Biology, pp. 1174-1175, Images of the Twenty-First Century - Proceedings of the 11th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2, Seattle, WA, USA, 11/9/89.
Benke TA, Clark JW, Wisoff PJ, Shehab SA, Schneider S, Chidambaram B et al. Electrophysiological and histological studies of laser and suture anastomosis in rat sciatic nerve. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 11 pt 4. Publ by Alliance for Engineering in Medicine & Biology. 1989. p. 1174-1175
Benke, T. A. ; Clark, J. W. ; Wisoff, P. J. ; Shehab, S. A. ; Schneider, S. ; Chidambaram, B. ; Hawkins, H. ; Laurent, J. / Electrophysiological and histological studies of laser and suture anastomosis in rat sciatic nerve. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 11 pt 4 Publ by Alliance for Engineering in Medicine & Biology, 1989. pp. 1174-1175
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