Embryology of the craniocervical junction and posterior cranial fossa

Mohammadali M. Shoja, R. Shane Tubbs, W. Jerry Oakes

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


The development of the craniocervical junction is a complex sequence that requires perfect arrangement between cranial and cervical components. The neural crest cells of the upper somites and the notochord are both important in the development of this region. Of particular significance is the proatlas. Recent molecular studies have increased our knowledge of the processes involved in the formation of the base of the skull and upper cervical spine. The orchestration of the developing rhombencephalon and craniocervical junction is critical in the proper adult neuro-osseous relationships. Derailment of these processes may result in hindbrain herniation.

Original languageEnglish (US)
Title of host publicationThe Chiari Malformations
PublisherSpringer New York
Number of pages42
ISBN (Electronic)9781461463696
ISBN (Print)1461463688, 9781461463689
StatePublished - Mar 1 2013
Externally publishedYes


  • Cerebellum
  • Craniovertebral junction
  • Embryology
  • Hindbrain herniation
  • Posterior fossa

ASJC Scopus subject areas

  • General Medicine


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