Abstract
The development of the craniocervical junction is a complex sequence that requires perfect arrangement between cranial and cervical components. The neural crest cells of the upper somites and the notochord are both important in the development of this region. Of particular significance is the proatlas. Recent molecular studies have increased our knowledge of the processes involved in the formation of the base of the skull and upper cervical spine. The orchestration of the developing rhombencephalon and craniocervical junction is critical in the proper adult neuro-osseous relationships. Derailment of these processes may result in hindbrain herniation.
Original language | English (US) |
---|---|
Title of host publication | The Chiari Malformations |
Publisher | Springer New York |
Pages | 13-54 |
Number of pages | 42 |
Volume | 9781461463696 |
ISBN (Electronic) | 9781461463696 |
ISBN (Print) | 1461463688, 9781461463689 |
DOIs | |
State | Published - Mar 1 2013 |
Externally published | Yes |
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Keywords
- Cerebellum
- Craniovertebral junction
- Embryology
- Hindbrain herniation
- Posterior fossa
ASJC Scopus subject areas
- Medicine(all)
Cite this
Embryology of the craniocervical junction and posterior cranial fossa. / Mohajel Shoja, Mohammadali; Tubbs, R. Shane; Oakes, W. Jerry.
The Chiari Malformations. Vol. 9781461463696 Springer New York, 2013. p. 13-54.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Embryology of the craniocervical junction and posterior cranial fossa
AU - Mohajel Shoja, Mohammadali
AU - Tubbs, R. Shane
AU - Oakes, W. Jerry
PY - 2013/3/1
Y1 - 2013/3/1
N2 - The development of the craniocervical junction is a complex sequence that requires perfect arrangement between cranial and cervical components. The neural crest cells of the upper somites and the notochord are both important in the development of this region. Of particular significance is the proatlas. Recent molecular studies have increased our knowledge of the processes involved in the formation of the base of the skull and upper cervical spine. The orchestration of the developing rhombencephalon and craniocervical junction is critical in the proper adult neuro-osseous relationships. Derailment of these processes may result in hindbrain herniation.
AB - The development of the craniocervical junction is a complex sequence that requires perfect arrangement between cranial and cervical components. The neural crest cells of the upper somites and the notochord are both important in the development of this region. Of particular significance is the proatlas. Recent molecular studies have increased our knowledge of the processes involved in the formation of the base of the skull and upper cervical spine. The orchestration of the developing rhombencephalon and craniocervical junction is critical in the proper adult neuro-osseous relationships. Derailment of these processes may result in hindbrain herniation.
KW - Cerebellum
KW - Craniovertebral junction
KW - Embryology
KW - Hindbrain herniation
KW - Posterior fossa
UR - http://www.scopus.com/inward/record.url?scp=84949180047&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84949180047&partnerID=8YFLogxK
U2 - 10.1007/978-1-4614-6369-6_3
DO - 10.1007/978-1-4614-6369-6_3
M3 - Chapter
AN - SCOPUS:84949180047
SN - 1461463688
SN - 9781461463689
VL - 9781461463696
SP - 13
EP - 54
BT - The Chiari Malformations
PB - Springer New York
ER -