Emergence of a new epidemic/epizootic Venezuelan equine encephalitis virus in South America

Rebeca Rico-Hesse, Scott Weaver, Julieta De Siger, Gladys Medina, Rosa Alba Salas

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

One of the most important questions in arbovirology concerns the origin of epidemic Venezuelan equine encephalitis (VEE) viruses; these viruses caused periodic, extensive epidemics/epizootics in the Americas from 1938-1973 (reaching the United States in 1971) but had recently been presumed extinct. We have documented the 1992 emergence of a new epidemic/epizootic VEE virus in Venezuela. Phylogenetic analysis of strains isolated during two outbreaks indicated that the new epidemic/epizootic virus(es) evolved recently from an enzootic VEE virus in northern South America. These results suggest continued emergence of epizootic VEE viruses; surveillance of enzootic viruses and routine vaccination of equines should therefore be resumed.

Original languageEnglish (US)
Pages (from-to)5278-5281
Number of pages4
JournalProceedings of the National Academy of Sciences of the United States of America
Volume92
Issue number12
DOIs
StatePublished - Jun 6 1995

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Venezuelan Equine Encephalitis Viruses
South America
Viruses
Venezuela
North America
Disease Outbreaks
Vaccination

Keywords

  • emerging virus
  • epidemiology
  • molecular evolution

ASJC Scopus subject areas

  • Genetics
  • General

Cite this

Emergence of a new epidemic/epizootic Venezuelan equine encephalitis virus in South America. / Rico-Hesse, Rebeca; Weaver, Scott; De Siger, Julieta; Medina, Gladys; Salas, Rosa Alba.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, No. 12, 06.06.1995, p. 5278-5281.

Research output: Contribution to journalArticle

Rico-Hesse, Rebeca ; Weaver, Scott ; De Siger, Julieta ; Medina, Gladys ; Salas, Rosa Alba. / Emergence of a new epidemic/epizootic Venezuelan equine encephalitis virus in South America. In: Proceedings of the National Academy of Sciences of the United States of America. 1995 ; Vol. 92, No. 12. pp. 5278-5281.
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